When it comes to cleaning products, enzymatic cleaners are among the best options available. Their ability to break down tough stains, odors, and organic matter makes them highly effective for various cleaning tasks around the house, especially for pet owners. In 2024, if you’re looking for the best enzymatic cleaner, you’ll want to check out the top 10 enzymatic cleaners available on Amazon. Here, we will review these products, highlighting their unique features and benefits, while also providing a comprehensive buying guide to help you make an informed choice.
- Certified Gentle And Safe: Chlorine free and color safe; Safe to use around pets and children; No hazardous propellants, no residue left behind. So gentle it’s been Certified Safe for all carpets, earning the Seal of Approval by the trusted Carpet and Rug Institute (cri)
- Eliminates Stains, Odors and Residue: If it’s gross, it’s gone; Not just the stain, but the stink; From stinky yellow pet urine and feces to vomit and other organic spills, our professional strength formula tackles them all
- Every Surface, Every Time: For use on carpets, floors, furniture, clothing, litter boxes, kennels, carriers, all pet living and sleeping areas—anywhere stains happen
- Enzyme Activated: The key is getting to the problem deep-down; This spray contains natural enzymes that are activated on contact with odors and stains, feeding on ammonia crystals and organic matter until they are completely eliminated
- Buy With Confidence: You want the best for your best friend; We do, too; If you are not satisfied with the performance of this product, contact us; We are determined to make it right
- 1 gallon bottle of multi-purpose enzyme cleaning solution for a wide variety of surfaces and environments
- Breaks up complex organic proteins, pet smells and stains, hair, grease, oils, and more for effective results
- Ideal for commercial properties, retail, and hospitality
- Use as needed on stains and problem areas for spot cleaning carpet, surfaces, drains, toilets, grease traps, and more
- SPOT STAIN & ODOR REMOVER: Begins to break down and remove stains immediately on contact.
- LIGHT CITRUS SCENT: Dog odor control formula gets your home smelling clean again.
- ENZYMATIC FORMULA: Continues working as long as any bio-based mess is still present.
- TRUSTED BRAND: From the maker of Nature’s Miracle products, the pet stain and odor removing brand you trust… because it works!
- SAFE FOR PETS AND HOME: When used and stored as directed, this formula can be used around your pets.
- THE POWER OF ONE: This versatile product is the only probiotic cleaner you need, providing powerful cleaning performance in a wide variety of applications. Multipurpose use: Maintain clean drain lines and septic tanks to prevent clogs and potential buildup. Clean and deodorize trash bins, stains and odors on floors, carpets, bathroom surfaces, kitchen surfaces, and more.
- ACTIVE UP TO 21 DAYS: Our specialized probiotics continue to clean soils in cracks, grout and tough to reach places. Simply spray & let the probiotics do the dirty work!
- NATURALLY, SUPERIOR RESULTS: A special blend of enzyme-producing probiotics break down complex proteins, fats, oils, greases, and other organic waste. The enzymes digest the soils until they have been eliminated, providing a long-lasting, continuous clean without leaving a residue or harmful by-products behind.
- ELIMINATE ODOR: Provide total odor control by eliminating the actual source of even the most pungent organic malodors naturally, including rotting food, urine, feces, vomit, and trash. Plus, the fresh lemon and sage fragrance leaves behind a light, pleasant scent that rejuvenates the air of any environment.
- MADE IN THE USA - 1 Gallon Bottle
- PET STAIN AND ODOR REMOVER: Things can get a little messy when your pet is involved - that’s where we come in; This extra-strength cleaning solution is specially formulated to tackle the toughest smells & dirtiest spots left behind by your beloved pets.
- EXTREME ENZYMATIC CLEANER: This professional strength spray consists of a powerful enzyme formula three times stronger than our regular formula, specialized for breaking down, eliminating, and permanently neutralizing both new and old stains and odors.
- FOR DOGS AND CATS: Say goodbye to bad messes - This dog and cat-specific cleaning spray is the best thing for cleaning up after urine, feces, vomit, and all the stains and smells that accompany them; It is a pet-safe and family-friendly cleaning option
- MULTIFUNCTION SPRAY: This cleaner can be used for carpets, upholstery, bedding, fabric toys, clothing, & other water-safe surfaces in your home; It uses a patented 3-in-1 nozzle with mist, foam, and stream features so you can pick the best way to clean up
- SIMPLE SOLUTION: it’s just that…a simple solution to all of your pets’ messes – wherever they may be; We offer easy-to-use, no-hassle products that will effectively help you keep your home clean and sparkling; In short - pet parenting made easy.
- FOR SEVERE DOG MESSES: Powerful enzymatic formula works to eliminate tough stains and odors from dog urine, diarrhea, vomit and other bio-based accidents.
- LIGHT FRESH SCENT: Dog odor control formula gets your home smelling clean again.
- ENZYMATIC FORMULA: Continues working as long as any bio-based mess is still present.
- DISCOURAGES RESOILING: Removes the odor from even the toughest dog messes.
- TRUSTED BRAND: From the maker of Nature’s Miracle products, the pet stain and odor removing brand you trust because it works
![McKesson Multi-Enzymatic Cleanser for Surgical Instruments & General Healthcare Equipment, 1 Gallon [Pack of 1] Fresh Mint](https://m.media-amazon.com/images/I/315++WOcrzL.jpg)
- McKesson multi-enzymatic detergent contains a synergistic combination that effectively removes bodily fluids and tissues from medical equipment
- Instrument detergent is non-foaming with a neutral pH for easy use; 100 percent biodegradable and environmentally friendly
- Instrument cleaning detergent is non-abrasive and won't harm plastic, metal, rubber or corrugated tubing; surgical instruments can pre-soak for manual cleaning or the first step of automatic cleaning
- Eucalyptus spearmint scent offers refreshing blend of sharp mint and fresh citrus notes
- Detergent comes in a 1 gallon jug
- ✅ COMBAT ORGANIC MESSES : Enzyme cleaner emits enzymes to break down molecules found in organic material like grass, blood, urine, vomit feces, and food. Once it breaks the molecules down into smaller pieces, the raising agent swoops in to consume those molecules.
- ✅ MULTI-PURPOSE: Proprietary blend of enzymes breaks up complex organic proteins, pet stains, hair, grease, fats, and oils, easily cutting through dirt, grease, and grime without leaving any visible residue. Don't just expect clean, expect Enzyme Clean!
- ✅ MULTI-SURFACE: Nanoskin Enzyme has a special blend of beneficial enzymes, detergent, and deodorant, prevents clogging in drains, grease traps, septic tanks, drain lines, and downpipes and cleans stains, odors, carpets, floors, kitchen & bathroom surfaces, and much more. Ideal for professional detailer and home use.
- ✅ ELIMINATE FOUL ODORS: Effectively eliminates foul odors caused by urine, feces, blood, vomit, food, garbage, and grease and leaves long-lasting freshness. Nanoskin Enzyme is fragrance free with no artificial fragrance to cover the odor. Safe to use around pets and children.
- ✅ EASY & SAFE TO USE: Ready-to-Use formula. Nanoskin Enzyme is formulated to be safe & effective, non-corrosive, non-flammable, non-acidic, free of caustics and staining dyes, pH neutral, paraben-free. Unique proprietary solutions, trusted by professionals and consumers.
- FOR DOG URINE MESSES: Begins to break down and remove stains immediately on contact.
- POWERFUL FORMULA: Just soak the affected area, allow to work for 15 minutes, then blot up stain with a clean cloth.
- ENZYMATIC FORMULA: Continues working as long as any bio-based mess is still present.
- MADE WITH RECYCLED MATERIAL: Our bottles are made with 25% Post-Consumer Recycled Material.
- SAFE FOR PETS AND HOME: When used and stored as directed, this formula can be used around your pets and in your home
- Pro Grade Clean - Zeiff Pro-Grade Formulas are innovative, unique proprietary solutions, trusted by professionals and consumers for being the most effective cleaning products to get the job done. Whether you’re a pro or just expect pro-grade results, Zeiff delivers Pro Grade Clean
- Powerful Cleaning Performance - Our super strength proprietary formulation breaks up and digests complex organic proteins, pet stains, hair, grease, fats, and oils, easily cutting through dirt, grease and grime without leaving any visible residue. Don't just expect clean, expect Zeiff Clean! You'll know it when you see it, clean you didn't even know exists
- Multi-Purpose Enzyme Cleaner - The drain odor eliminator is a special blend of powerful bacterial enzymes, detergent and deodorant, that prevents clogging in drains, garbage disposals, grease traps, sinks, toilets, urinals, septic tanks, drain lines and downpipes. The floor and carpet stain remover cleans stains, odors, carpets, upholstery, fabric, laundry, floors, hardwood, laminate, kitchen & bathroom surfaces, and much more. Ideal for Professional and Home use
- Deodorizer & Odor Eliminator - The dog enzyme cleaner and pet odor eliminator for home is a highly concentrated bacterial digestant for grease, stains, oils, & organic waste. The pet urine enzyme cleaner effectively eliminates foul odors caused by urine, feces, blood, vomit, food, garbage and grease, leaves long-lasting freshness, with a subtle citrus breeze that instantly refreshes any space with a pleasant aroma, great pet enzyme urine cleaner and cat odor eliminator
- Safe & Effective - Zeiff Pro Grade Formulas are safe & effective, non-corrosive, non-flammable, non-acidic, free of caustics and dyes, pH neutral, paraben-free, pet safe, cruelty-free. Proudly made in the USA
Top 10 Best Enzymatic Cleaners on Amazon
1. Nature’s Miracle Stain & Odor Remover
Nature’s Miracle has established itself as a go-to brand for pet owners seeking effective cleaning solutions. This enzymatic cleaner targets tough stains and odors caused by pets, using natural enzymes to break down organic waste. It’s ideal for carpets, hard floors, and furniture upholstery. Many users rave about its ability to eliminate even the strongest pet-related odors, making it a top contender for the best enzymatic cleaner.
This product is also non-toxic and safe to use around pets and children, ensuring peace of mind while cleaning.
- SPOT STAIN & ODOR REMOVER: Begins to break down and remove stains immediately on contact.
- LIGHT CITRUS SCENT: Dog odor control formula gets your home smelling clean again.
- ENZYMATIC FORMULA: Continues working as long as any bio-based mess is still present.
- TRUSTED BRAND: From the maker of Nature’s Miracle products, the pet stain and odor removing brand you trust… because it works!
- SAFE FOR PETS AND HOME: When used and stored as directed, this formula can be used around your pets.
2. Rocco & Roxie Professional Strength Stain Remover
Rocco & Roxie’s Professional Strength Stain Remover is another top choice for pet owners. This cleaner features a powerful formula that penetrates deep into carpets and upholstery to break down stains and odors. Its enzymatic action guarantees that even the most stubborn messes are dealt with effectively. The product is also free from harsh chemicals, making it safe for daily use in homes with pets and children.
This cleaner gets high marks for its effectiveness on both old and new stains, offering versatility that many pet owners appreciate.
- Eliminates Major Stains, Odors, and Residue: If it’s gross, it’s gone; From blowouts, urine, vomit, and other organic spills, our extreme formula tackles them all; Formulated with a subtle Meyer lemon scent that quickly dissipates, leaving your space feeling fresher than before
- Every Surface, Every Time: Our fast-acting formula works great on carpets, floors, furniture, clothing, pet bedding, litter boxes, travel crates, hamster cages, cars, campers, and anywhere else major accidents happen
- Minerals, Meet Enzymes: The key is getting to the problem deep-down—so we added a mineral-based odor neutralizer to our potent bio-enzymatic formula; Activated on contact with tough stains and odors, it feasts on ammonia crystals and organic matter until they are completely eliminated
- Certified Gentle and Safe: Chlorine free and color safe. Safe to use around pets and children, when used as directed; No hazardous propellants, no residue left behind; So gentle it’s been Certified Safe for all carpets, earning the Seal of Approval by the trusted Carpet and Rug Institute (CRI)
- Buy With Confidence: You want the best for your best friend; We do, too; If you are not satisfied with the performance of this product, contact us; We are determined to make it right
3. Biokleen Bac-Out Stain Remover
Another fantastic enzymatic cleaner is Biokleen Bac-Out Stain Remover. This product contains live enzyme cultures and is designed to break down organic stains and odors effortlessly. It can be used on a variety of surfaces, including carpets, upholstery, fabric, and even laundry. Customers often highlight its effectiveness on both pet stains and general spills, positioning it as a versatile addition to any cleaning arsenal.
Moreover, Biokleen prides itself on being eco-friendly and free of artificial fragrances and color additives, which is a major plus for environmentally conscious consumers.
- biokleen Bac Out Stain & Odor Eliminator with Live Enzyme Cultures, 32 oz
4. Simple Green Pro 5 Cleaner
Simple Green Pro 5 Cleaner is a professional-grade enzymatic cleaner that can tackle tough grease, oil, and stains with ease. It’s not only beneficial for pet owners but also ideal for industrial use. This cleaner employs a powerful but safe enzymatic solution capable of breaking down stubborn substances on multiple surface types.
Users appreciate its versatility, as it works well on not just textiles but also hard surfaces, making it a favorite for industrial cleaning professionals.
- Simple Green d Pro 5 is a one-step disinfectant that has a high level of active ingredients for heightened efficacy and economy
- It can be used in food production, processing, and service facilities
- Simple Green d Pro 5 has an extensive efficacy list including Hepatitis B and C, Canine Distemper Virus, and Avian Influenza
- Simple Green d Pro 5 is meant to be absolutely effective on the bacterial, viral, and fungal threats that invade our lives
- Ideal for athletic facilities, bars/restaurants, barber shops, bathrooms, beauty salons, business and office buildings, cafeterias, convenience stores, correctional facilities and day care centers
5. PetSafe Remove Odor and Stain Eliminator
For those who are looking for a product dedicated to combatting pet-related messes, the PetSafe Remove Odor and Stain Eliminator is worth considering. This enzymatic cleaner is specially formulated to eliminate odors and stains from pet urine, feces, blood, and vomit. It penetrates deep into surfaces to eliminate the source of the odor rather than just masking it.
Many users praise its efficiency in eliminating lingering odors and preventing pets from re-soiling the same area.
- Certified Gentle And Safe: Chlorine free and color safe; Safe to use around pets and children; No hazardous propellants, no residue left behind. So gentle it’s been Certified Safe for all carpets, earning the Seal of Approval by the trusted Carpet and Rug Institute (cri)
- Eliminates Stains, Odors and Residue: If it’s gross, it’s gone; Not just the stain, but the stink; From stinky yellow pet urine and feces to vomit and other organic spills, our professional strength formula tackles them all
- Every Surface, Every Time: For use on carpets, floors, furniture, clothing, litter boxes, kennels, carriers, all pet living and sleeping areas—anywhere stains happen
- Enzyme Activated: The key is getting to the problem deep-down; This spray contains natural enzymes that are activated on contact with odors and stains, feeding on ammonia crystals and organic matter until they are completely eliminated
- Buy With Confidence: You want the best for your best friend; We do, too; If you are not satisfied with the performance of this product, contact us; We are determined to make it right
6. OxiClean MaxForce Spray
OxiClean MaxForce Spray utilizes the power of OxiClean to tackle tough stains, but it also contains enzymes that help break down organic material. This makes it effective not just for food stains, but also for pet messes. Users love its ability to lift set-in stains and odors, making it a practical solution for both pre-treating laundry and cleaning carpets.
Its convenience in a spray bottle allows for easy application, making it an accessible option for quick clean-ups.
- The convenient 12 fl oz bottle 3-pack of OxiClean Max Force Laundry Stain Remover Spray tackles your stubborn and dried-in laundry stains
- OxiClean Max Force stain spray lets you pretreat stains now, then wash up to seven days later for cleaning that fits your schedule
- Powerful laundry spot remover for oil, grease, make-up, blood, grass, soil, clay, ink, food, drinks, and kid and baby stains
- Laundry stain remover for clothes is 100 percent dye free and chlorine free, and safe for use on all machine-washable whites and colored fabrics, even kid and baby clothes
- Spray directly on stains until saturated, let stand five minutes or up to seven days before washing with detergent in the warmest water garment will accept. For whiter, brighter clothes, add OxiClean Versatile Stain Remover to washer per label directions
7. Zorb-It-Up Odor Eliminator
Zorb-It-Up is a unique enzymatic cleaner designed to absorb and neutralize odors rather than just masking them. This product works exceptionally well in challenging situations, such as basement cleanup or other areas within the house where moisture or organic waste can create odors. Many users have reported that it can effectively eliminate musty smells as well.
The absorbent nature of this cleaner allows it to be a multi-faceted tool in your cleaning kit.
- INSTANT, PERMANENT, ADVANCED PATENTED MULTIPURPOSE ODOR REMOVAL FORMULA: We continue utilizing safer, superior, and more advanced odor removal technologies to provide our customers with the best products. With just a little splash of ZORBX odor remover, you will be able to tackle all kinds of odors like professionals no matter how strong they are. Our odor remover formula is the permanent solution to your odor problems.
- EXTRA STRENGTH, SAFER, ECO-FRIENDLY ODOR ABSORBERS FOR ROOMS: Non-toxic ingredients in ZORBX multipurpose odor remover are derived from natural resources. This odor remover is safer for people, pets, and the planet. Our unscented odor neutralizer will help remove foul and funky odors without harming you, your pet, or the planet. Our ZORBX odor eaters will make your surroundings and furry friends smell clean and fresh!
- 16 OZ SPRAY: Our odor remover comes in a convenient 16 oz. spray bottle, perfect for freshening up the air anywhere you go. Keep odor remover spray bottle in your car or travel bag to quickly eliminate unpleasant smells while on the go. Carpet odor remover is ideal for outdoor travel and everyday use at home, in garages, basements, and bathrooms.
- WHY BUY OUR PRODUCT? You must be wondering why choose our product when it's available in different sizes. Our product offers fast-acting smoke, urine, hospital odor remover solutions to help you breathe fresh air wherever you go. With this spray, you will never run out of odor exterminator solutions—the perfect spray for fighting all kinds of odors.
- TRUSTED BRAND: The main goal of our company ZORBX is to provide our customers with high-quality products. Also, all of our odor remover solutions are strictly inspected before we ship them out to you. If you are not happy with our strong odor remover for any reason, please contact us. We will take care of it in no time! Your satisfaction is our priority.
8. Bissell Pet Pro Oxy Stain Destroyer
Bissell’s Pet Pro Oxy Stain Destroyer is an enzymatic carpet cleaner formulated specifically for breaking down pet stains. With its unique dual-action formula, it not only cleans stains but also permanently neutralizes odors, making it a sought-after option for pet owners. Many users report that it outperforms competitors in treating embedded stains.
This product can be used with carpet cleaning machines or as a standalone spray, providing a flexible cleaning solution.
- EVERY PURCHASE SAVES PETS. Every purchase makes it possible for BISSELL to continue our support of BISSELL Pet Foundation and its mission of saving pets in need.
- INSTANT AND PERMANENT STAIN REMOVAL. Instantly and permanently removes tough stains like urine, mud, blood, pet stains, wine, food stains, and more!
- ELIMINATES TOUGH PET ODORS. BISSELL PET PRO OXY Stain Destroyer offers a long-lasting fresh scent while you clean.
- DESIGNED FOR HOMES WITH KIDS & PETS. Earth friendly formula with biodegradable detergents. Contains no heavy metals or dyes.
- ONE SPRAYER IS INCLUDED WITH TWO-PACKS. Please keep your sprayer and reuse it for the second bottle (simply remove the spray trigger from the first bottle and apply to the second).
9. ToughGrade Professional Pet Stain & Odor Remover
ToughGrade’s Professional Pet Stain & Odor Remover boasts an advanced formula that penetrates deep to dissolve and eliminate stains and odors. It’s popular among users for its effectiveness and fast-acting nature, making it ideal for emergency clean-ups. With a non-toxic formula, it’s also safe for use around kids and pets.
Many users appreciate its capacity to handle various surfaces, making it a versatile choice.
- Certified Gentle And Safe: Chlorine free and color safe; Safe to use around pets and children; No hazardous propellants, no residue left behind. So gentle it’s been Certified Safe for all carpets, earning the Seal of Approval by the trusted Carpet and Rug Institute (cri)
- Eliminates Stains, Odors and Residue: If it’s gross, it’s gone; Not just the stain, but the stink; From stinky yellow pet urine and feces to vomit and other organic spills, our professional strength formula tackles them all
- Every Surface, Every Time: For use on carpets, floors, furniture, clothing, litter boxes, kennels, carriers, all pet living and sleeping areas—anywhere stains happen
- Enzyme Activated: The key is getting to the problem deep-down; This spray contains natural enzymes that are activated on contact with odors and stains, feeding on ammonia crystals and organic matter until they are completely eliminated
- Buy With Confidence: You want the best for your best friend; We do, too; If you are not satisfied with the performance of this product, contact us; We are determined to make it right
10. Green Works Natural All-Purpose Cleaner
While not solely an enzymatic cleaner, Green Works Natural All-Purpose Cleaner contains biodegradable cleaning agents and enzymes. It’s great for general cleaning tasks around the house while still being tough on stains. Consumers love its pleasant scent and effectiveness on various surfaces, from kitchen counters to bathroom tiles.
This cleaner is best for those who want an eco-friendly option without sacrificing cleaning power.
- CLOROX ALL-PURPOSE CLEANER: Clorox EcoClean All-Purpose Cleaner cleans grease, dirt and soap scum from a variety of surfaces throughout the home and office
- MADE WITH 99% BIOBASED INGREDIENTS: This all-purpose cleaning spray meets US EPA Safer Choice Product standards and is a USDA Certified Biobased cleaner, made with 99% biobased ingredients
- USE ON A VARIETY OF SURFACES: Safe on multiple surfaces throughout the kitchen and bathroom, including counters, appliances, stainless steel, sealed granite, chrome, cooktop hoods, sinks and toilets
- FORMULATED WITHOUT BLEACH: This Clorox all-purpose cleaner is formulated without parabens, dyes, phthalates, phosphates, petroleum solvents and SLES
- GREAT FOR COMMERCIAL USE: Clorox EcoClean All-Purpose Cleaner effectively cleans without harsh chemical odors, fumes or residues and is safe for use around food contact surfaces*
Buying Guide for Enzymatic Cleaners
When searching for the best enzymatic cleaner, it’s essential to consider several factors to ensure you choose a product that meets your specific needs. Here are some key aspects to look at:
1. Purpose
Identify what you primarily need the enzymatic cleaner for—pet stains, food spills, mold, or general cleaning. Different products excel in various areas, so choose one aligned with your requirements.
2. Surface Compatibility
Check whether the cleaner is suitable for the surfaces you plan to clean. Some products work well on carpets and upholstery, while others may be more effective on hard surfaces.
3. Ingredients
Opt for enzymatic cleaners that utilize natural, non-toxic ingredients if you have children or pets at home. This will ensure a safer cleaning experience.
4. Scent
Many enzymatic cleaners are fragrance-free or use essential oils for scent. Choose one that fits your preferences, especially if strong fragrances may be overpowering.
5. User Reviews
Before making a purchase, read user reviews to gauge product effectiveness based on real-world experiences. Look for feedback regarding odor control, stain elimination, and overall satisfaction.
6. Price
Finally, consider your budget. While some products may cost a bit more, the effectiveness could save you money on repeated purchases or professional cleaning services.
In conclusion, finding the best enzymatic cleaner can significantly simplify your cleaning routine. With the right choice, you can ensure your home stays fresh, clean, and free from pesky stains and odors. Whether you’re a pet owner or simply looking for an effective cleaner, the products reviewed above cater to a wide variety of needs.
Last update on 2025-03-20 / Affiliate links / Images from Amazon Product Advertising API | votechriscarrillo.com is a participant in the Amazon Associate program and will earn from qualifying purchases.