If you’re on the lookout for the best vitamin B12 supplement, you’ve arrived at the right spot! In this comprehensive guide, we delve into the top 10 vitamin B12 supplements available on Amazon in 2025. These products have been selected based on customer reviews, efficacy, and overall quality. Whether you’re vegan, vegetarian, or just looking to maintain optimal health, our detailed reviews will help you find the best vitamin B12 supplement that suits your needs.
- Energy metabolism support supplement: contains one 150 count bottle of Nature Made Vitamin B12 1000 mcg Softgels for a 150 day supply(1)
- These Nature Made Vitamin B12 softgels help break down food into energy that your body can use all day long
- B-12 vitamin helps support brain cell function and mood health (2)
- Vitamin B12 is important for proper red blood cell formation and helps reduce fatigue for those low in B12 vitamins
- Adults take one B 12 vitamin softgel daily with water and a meal
- SUPPORTS CELLULAR ENERGY HEALTH (1): Nature's Bounty Vitamin B-12 1000 mcg aids in converting food into cellular energy (1)
- CARDIOVASCULAR SUPPORT (1): Vitamin B-12 supplements contribute to the health of your cardiovascular and circulatory systems (1)
- MAINTAINS HEALTHY NERVES (1): Great for nerve health, B-12 vitamin helps maintain healthy nerve cells (1)
- EASY TO SWALLOW: These Vitamin B-12 tablets are coated so they are easy to swallow, providing convenience in your daily vitamin regimen
- TRUSTED WELLNESS: From trusted wellness experts, these B-12 Vitamins are made with quality ingredients, backed by 50 years of scientific research
- Active B12: Each capsule provides 1 mg vitamin B12 as methylcobalamin, which is more efficiently used by the body compared to other forms of vitamin B12, like cyanocobalamin
- Heart & Brain Health: Supports a normal level of homocysteine in the body to benefit healthy cardiac function, blood cell formation, and optimal nerve function*
- Sleep Support: Helps maintain normal circadian rhythms to support restful sleep and supports healthy methylation processes in the body*
- Third-Party Certified: This product has been third-party tested and certified to verify what's in the package matches what's on the label and to confirm it contains no unsafe levels of contaminants
- Trusted: Thorne is chosen by champions and trusted by 100+ professional sports teams, a proud partner of U.S. National Teams, and the #1 recommended clinical brand by health-care practitioners (2023 Health-Care Practitioner Seller Survey)
- B12 Drops Formulated for Maximum Potency - Our Liquid Vitamin B12 Drops contain Vit B12 5000mcg, B6, B1, Niacin, and Folic Acid, supporting overall body functions with 100% or more Daily Value.
- Tons of Benefits - Experience the synergy of brain support, digestive balance, energy metabolism, heart wellness, and immune support in each drop of our Vitamin B complex liquid sublingual formula.
- Rapid Sublingual Absorption - Our Liquid B12 Drops are designed for efficient sublingual absorption. Just place the drops under your tongue for 30secs and swallow the remaining liquid. Quick and easy!
- Carefully Curated Organic Vitamin B12 Liquid - Our Vitamin B12 Methylcobalamin B6 B1 Drops contain No Fillers, are Vegan, Non-GMO, Gluten-Free, and proudly USA-made with Global Ingredients.
- Ultimate 5-in-1 Vitamin B12 Complex - Not all liquid supplements are made equal. Our B-12 Vitamin drops are packed with nutritional benefits. Each has 27,200 mcg. If you’re unhappy with your purchase, do reach out to us.
- 240 Capsules of Vitamin B12 In Each Bottle
- 2,000mcg of Vitamin B12 (Methylcobalamin) in each (Vegetarian) Capsule
- High Quality B12, Vegetarian Friendly, Non-GMO, Gluten Free
- Tested by Independent (3rd Party), ISO-Accredited Laboratories
- Made in a GMP Compliant, FDA Registered Facility
- Vitamin B12 Supplement: EZ Melts B12 are dissolvable tablets that deliver 2,500 mcg of vitamin B12 per serving for easy metabolic energy support*
- Energy Support Supplement: Supports healthy energy levels, cellular health, and natural energy production to support overall wellness*
- Brain Health Supplement: Methylcobalamin B12 is essential to help maintain focus and cognitive function, so you can stay alert when it matters most*
- Mood Support Supplement: Supports nervous system function, which helps maintain clarity*
- Non-GMO & Vegan Supplement: EZ Melts makes it easier to take superior quality vitamins—free from artificial flavors, gluten, dairy, soy, and sugar
- Energy metabolism support supplement(1): contains one 160 count bottle of Nature Made B12 1000mcg Time Release Tablets for a 160-day supply
- Nature Made B12 1000 mcg dietary supplements provide B12 to help break down food into energy that your body can use all day long
- B-12 vitamin helps support brain cell function and mood health (2)
- Vitamin B12 is important for proper red blood cell formation and helps reduce fatigue for those low in vitamin B-12
- Time release formula extends vitamin absorption by the body; Adults take one Nature Made B12 timed release tablet daily with water and a meal
- Premium Folate Supplement: Vitamin B12 and folate help convert carbohydrates into energy and break down proteins in the body; provides metabolism support*
- Nervous System Support: Vitamin B12 (methylcobalamin) and folate (L-5-MTHF) support the nervous system, and function as hair, skin, and liver aids.*
- Cognitive Support: Folate is essential for fetal neural development; B12 is an important nutrient for memory and cognitive support*
- Supports Gut Health: Support G.I. tract thanks to the active form of the B12 vitamin, methylcobalamin; also a liver support supplement*
- Pure Difference: What we leave out matters, too; Pure Encapsulations products are free from common allergens, artificial or unnecessary ingredients, and GMOs
- VITAMIN B12 FOR CELLULAR ENERGY (1): Natrol Fast Dissolve B12 vitamins 5000 mcg energy supplements help support energy metabolism and a healthy nervous system(1)
- FAST DISSOLVE SUPPLEMENT: These vit B12 5000 mcg tablets are easy to take; put in mouth on tongue and the fast dissolve formula will not need water
- SUPPORTS RED BLOOD CELL FORMATION(1): B 12 vitamin is essential for healthy red blood cell formation and provides cellular energy support(1)
- 100% DRUG-FREE B12 SUPPLEMENTS: This fast dissolving, 100% drug-free dietary supplement provides Vitamin B12 tablets for up to a 100 day supply; great for all wellness enthusiasts or those who travel and are looking to support energy metabolism (1)
- #1 DRUG FREE SLEEP AID BRAND IN AMERICA(2): As the #1 drug-free sleep aid brand, we provide formulas to help you fall asleep faster while offering fast-acting vitamin B12 supplements that help the body’s natural energy production process (1)
![NatureWise Vitamin B12 1000 mcg - Dietary Supplement for Supporting Energy Metabolism, Mental Clarity, Nervous System Health - Easy-to-Swallow, Soy & Gluten-Free, Non-GMO - 60 Softgels[60-Day Supply]](https://m.media-amazon.com/images/I/31IJJrz9ABL.jpg)
- ENERGY METABOLISM SUPPORT: Every easy-to-swallow softgel delivers 1000 mcg of Vitamin B12 to support the production of cellular energy and help convert food into energy.*
- CARDIOVASCULAR HEALTH: Vitamin B12 is important for cardiovascular health, function, and balance in homocysteine levels.*
- BRAIN & NERVE HEALTH SUPPORT: Vitamin B12 may support your cognitive function due to its important role in the nervous system. B12 contributes to the body's production of neurotransmitters, which affect clarity, mood, and memory.*
- SUPERIOR FORMULATION WITH HALAL GELATIN: NatureWise Vitamin B12 softgels have no artificial colors, synthetic dyes, flavors, or GMOs, and they are made with halal gelatin. They are free of gluten, wheat, soy, dairy, eggs, peanuts, tree nuts, fish, or shellfish.
- NSF-CONTENTS CERTIFIED, 3rd PARTY TESTED, QUALITY ASSURED: NatureWise Vitamin B12 1000 mcg softgels are 3rd party tested and NSF-Contents Certified for purity and efficacy and manufactured in the USA with high-quality ingredients from around the world in a cGMP-certified facility.
Importance of Vitamin B12
Vitamin B12, also known as cobalamin, plays a vital role in maintaining the health of your nerves and red blood cells, as well as DNA synthesis. A deficiency in B12 can lead to anemia and neurological issues. This is particularly essential for vegetarians and vegans, as B12 is predominantly found in animal products. Therefore, choosing the best vitamin B12 supplement can make a significant difference in your overall health.
Buying Guide for the Best Vitamin B12 Supplement
Understanding Types of B12
Before diving into our product reviews, it’s essential to understand the types of B12 supplements available:
- Methylcobalamin: A preferred form due to its immediate bioavailability and utility in the body.
- Cyanocobalamin: A commonly found synthetic type that the body converts to the active forms.
- Adenosylcobalamin: A mitochondrial form of B12 that is important for energy metabolism.
Factors to Consider
- Form of B12: Choose the form that suits your needs and preferences.
- Dosage: Check the concentration to ensure it meets your daily requirements.
- Additives: Look for fillers or potential allergens like gluten or soy.
- Certification: Look for NSF or USP certifications for quality assurance.
- Customer Reviews: High ratings and positive feedback can indicate effectiveness.
Now, let’s dive into the top 10 vitamin B12 supplements available on Amazon in 2025.
1. Nature Made Vitamin B12 1000 mcg
Nature Made is a well-known brand in the vitamin industry, and its Vitamin B12 supplement is popular among consumers. Each tablet contains 1000 mcg of Cyanocobalamin, making it an excellent option for those who need a high dosage.
Pros:
- High concentration of B12.
- Free from artificial flavors or colors.
- Easy to swallow tablets.
Cons:
- Contains Cyanocobalamin, which some might not absorb as well as Methylcobalamin.
This vitamin B12 supplement from Nature Made is available at an affordable price point, making it accessible for most consumers.
- Energy metabolism support supplement: contains one 150 count bottle of Nature Made Vitamin B12 1000 mcg Softgels for a 150 day supply(1)
- These Nature Made Vitamin B12 softgels help break down food into energy that your body can use all day long
- B-12 vitamin helps support brain cell function and mood health (2)
- Vitamin B12 is important for proper red blood cell formation and helps reduce fatigue for those low in B12 vitamins
- Adults take one B 12 vitamin softgel daily with water and a meal
2. MaryRuth Organics Vegan B12 Spray
MaryRuth Organics has created a unique vegan B12 spray that utilizes Methylcobalamin for better absorption. This formula is designed for those on a plant-based diet and offers a convenient spray option that is easy to take on the go.
Pros:
- Vegan-friendly formula.
- Methylcobalamin for better absorption.
- Convenient spray form.
Cons:
- Can be pricey compared to tablets.
This B12 spray is an excellent option if you’re looking for a quick and efficient way to boost your B12 levels.
- Boost Energy and Brain Health with B12 Vitamins: Our USDA Organic Vegan B12 Spray maintains normal energy levels and supports brain health! Ideal for those with an MTHFR gene variant; enjoy the benefits of vitamin B12 without compromising your diet—an effortless way to incorporate a b12 supplement into your wellness routine with a delicious berry flavor, supporting your brain, nervous system, and red blood cells!
- Travel-friendly :Perfect for busy travelers; ensure you never miss a b12 vitamin intake again with our compact spray that fits effortlessly into any handbag or backpack, providing a quick and convenient boost to your energy levels and mood, anytime, anywhere.
- Vegan : Integrate into your vegan lifestyle effortlessly; our vegan B12 formula supports cognitive function, and provides energy to those who are deffiicent. B12 also aids the body in DNA synthesis and red cell production. If you have an MTHFR gene variant, like MaryRuth herself, this might be the best type of B12 for you!
- Enhanced Absorption: Our natural berry flavored B12 Spray is made with methylcobalamin, which has superior bioavailability to cyanocobalamin! B12 also aids the body in DNA synthesis and red blood cell production.
- For Most Lifestyles: MaryRuth's Methyl B-12 vitamin Spray is USDA Organic, Vegan, Non-GMO, Dairy Free, Nut Free, Gluten Free, Soy Free, Sugar Free, Made in a GMP Facility. Clean Label Project Certified. B Corp Certified.
3. Solgar Vitamin B12 1000 mcg
Solgar’s Vitamin B12 is formulated with Methylcobalamin, offering superior absorption. Each tablet contains 1000 mcg, ideal for those who may need a higher intake due to dietary restrictions or deficiency risks.
Pros:
- Methylcobalamin for better absorption.
- Gluten-free and vegan-friendly.
- High quality and brand reputation.
Cons:
- Higher price range compared to other brands.
Overall, Solgar’s Vitamin B12 is an excellent option, especially for those who prioritize quality in their supplements.
- Energy Support; Vitamin B12 is part of a group of essential nutrients known as the B Complex; It supports energy metabolism and promotes a healthy nervous system
- Supports Heart Health; B12 supports heart health by promoting healthy levels of homocysteine already within a normal range; It also assists in the regeneration of red blood cells, which help to deliver oxygen throughout the body
- Convenient Dosage; Solgar Sublingual 1000 mcg Vitamin B12 nuggets melt under the tongue for fast, easy absorption
- Non-GMO, Kosher & Gluten Free; Solgar Vitamin B12 nuggets are suitable for vegans; Free of: gluten, wheat, dairy, soy, yeast, sugar, sodium, artificial flavor and color
- The Gold Standard: For over 70 years, Solgar has been committed to quality, health, and well-being. Our mission is to create the finest nutritional supplements in small batches, through tireless research, using only the finest raw materials
4. Garden of Life mykind Organics B12 Spray
This organic vitamin B12 spray from Garden of Life utilizes Methylcobalamin and is certified organic and non-GMO. It’s suitable for vegetarians and offers a great option for those who prefer a liquid form.
Pros:
- Organic and non-GMO certified.
- Methylcobalamin for increased bioavailability.
- Delicious flavor.
Cons:
- Slightly more expensive than traditional tablets.
This supplement is not only effective but pleasant to take, making it a solid option for anyone looking for a natural B12 source.
- ENERGY SUPPLEMENT: One spray daily delivers 500 Microgram (8333percentage DV) vegan vitamin B12 as methyl cobalamin to support energy, metabolism, and heart health*
- VITAMIN B12: Essential to protect the body against anemia and support a healthy central nervous system, B12 vitamin helps maintain healthy nerve cells and red blood cells and is also needed to make DNA, the genetic material in all cells*
- CONCENTRATION SUPPLEMENT: This whole food B12 concentration spray are made from real, nutritious foods
- LIQUID VITAMIN: Our organic liquid vitamin B12 comes in delicious, mouth watering raspberry spray
- ORGANIC VITAMIN: Our real food B12 vitamin is Certified USDA Organic, Non GMO Verified, Vegan, Gluten Free Certified, and Kosher Made
5. Jarrow Formulas Methyl B12 5000 mcg
For those needing a high-dose option, Jarrow Formulas provides a potent Methylcobalamin supplement with 5000 mcg per serving. One tablet can provide a significant boost to your B12 levels.
Pros:
- Very high dosage for immediate impact.
- Methylcobalamin form for better absorption.
- Vegetarian-friendly.
Cons:
- The high dosage may not be suitable for everyone.
This product is excellent for those who know they are deficient or those at risk of deficiency due to dietary limitations.
- Cellular Energy Production and Brain Health support supplement: Contains one 60 count bottle of Jarrow Formulas Maximum Strength Methyl B-12 5000 mcg Chewable Tablets for a 60-day supply.
- Each cherry-flavored chewable tablet provides a high amount of Methyl B-12 for benefits such as helping to support cellular energy production, maintaining brain health, and sleep.
- Methyl B-12 is better absorbed and retained by the body than cyanocobalamin, providing nutritional support for people with Vitamin B12 deficiency, vegetarians, vegans, and people over 50.
- Suggested Use: Adults, take one chewable tablet once a day or as directed by your qualified healthcare professional.
- These statements have not been evaluated by the Food and Drug Administration; this product is not intended to diagnose, treat, cure, or prevent any disease.
6. Life Extension Methylcobalamin B12 5000 mcg
Life Extension offers another high-dosage option with its Methylcobalamin B12. This supplement is designed for those who prioritize absorption and bioactivity.
Pros:
- Methylcobalamin for better bioavailability.
- Highly rated for quality.
- Gluten-free.
Cons:
- Higher potency may require more careful monitoring.
This option is particularly favorable for people who are aware of their B12 needs and wish to address deficiencies efficiently.
- B12 for brain health – B12 is a water-soluble vitamin that plays a vital role in nerve and brain health and cognitive function. Our B12 formula delivers the active form (methylcobalamin).
- Methylcobalamin for a healthy heart – Our B12 supplement is formulated to help promote cardiovascular health by supporting homocysteine levels already in the normal range.
- Quick-dissolving B12 lozenges – Getting your vitamin B12 has never been easier: our vitamin B12 supplement delivers 5 mg of methylcobalamin in every gluten-free, vegetarian lozenge.
- Ingredients matter – We use the finest raw ingredients with the quality and purity you deserve. The majority of our products are non-GMO, gluten-free and manufactured in the USA—and a Certificate of Analysis is available for every one.
- Live your healthiest life – We believe the answers to a healthier life are in reach, and that scientific research is the key to getting there. That’s why so many of our formulas feature specific ingredients and amounts based on scientific studies.
7. Nutricost Vitamin B12 5000 mcg
Nutricost offers a straightforward Vitamin B12 supplement that provides 5000 mcg of Methylcobalamin per serving. It’s an affordable choice for anyone looking for high-dose B12 without added frills.
Pros:
- Straightforward formula without fillers.
- High dosage at a reasonable price.
- Vegetarian-friendly.
Cons:
- Limited flavor options.
This product is an excellent value option for someone who wants a no-nonsense approach to B12 supplementation.
- 5000mcg (5mg) of Vitamin B12 Per Serving
- 240 Servings Per Bottle, 1 Capsule is 1 Serving
- Vegetarian, Non-GMO & Gluten Free
- Each Batch is Tested by Independent, ISO-Accredited Laboratories
- Made in an NSF Certified, GMP Compliant, FDA Registered Facility.
8. Kirkland Signature Vitamin B12 1000 mcg
Kirkland’s Vitamin B12 is another great choice, especially for bulk buyers as it offers a larger quantity at a very affordable price. This supplement includes 1000 mcg of Cyanocobalamin per tablet.
Pros:
- Economical choice for daily supplementation.
- Efficient dosage for most adult needs.
- Widely trusted brand.
Cons:
- Cyanocobalamin may not be as easily absorbed as Methylcobalamin.
This product stands out for those looking to stock up on their vitamins without breaking the bank.
- This advanced strength formula contains the highly bioavailable methylcobalamin form of B-12. This is an active form of B-12 as it does not need to be converted.
- Helps facilitate energy production*
- Supports a healthy nervous system*
- Supports healthy brain function*
- Please read all label information on delivery
9. Thorne Research Methylcobalamin B12 1000 mcg
Thorne Research is known for its high-quality formulations. Their Methylcobalamin B12 is no exception and offers 1000 mcg of one of the most bioavailable forms of B12. This product is especially appealing to health-conscious consumers.
Pros:
- High-quality ingredients with no unnecessary fillers.
- Methylcobalamin for optimal absorption.
- Good brand reputation among healthcare practitioners.
Cons:
- Premium price point.
This product is perfect for those who prioritize premium formulations and are willing to invest a bit more in their health.
- Active B12: Each capsule provides 1 mg vitamin B12 as methylcobalamin, which is more efficiently used by the body compared to other forms of vitamin B12, like cyanocobalamin
- Heart & Brain Health: Supports a normal level of homocysteine in the body to benefit healthy cardiac function, blood cell formation, and optimal nerve function*
- Sleep Support: Helps maintain normal circadian rhythms to support restful sleep and supports healthy methylation processes in the body*
- Third-Party Certified: This product has been third-party tested and certified to verify what's in the package matches what's on the label and to confirm it contains no unsafe levels of contaminants
- Trusted: Thorne is chosen by champions and trusted by 100+ professional sports teams, a proud partner of U.S. National Teams, and the #1 recommended clinical brand by health-care practitioners (2023 Health-Care Practitioner Seller Survey)
10. Source Naturals Vegan B12 1000 mcg
Source Naturals provides a vegan-friendly Vitamin B12 supplement that contains 1000 mcg of Methylcobalamin per tablet. This is a great option for anyone adhering to a plant-based diet.
Pros:
- Vegan and vegetarian-friendly.
- Methylcobalamin for superior absorption.
- Affirmed quality standards.
Cons:
- Some users may prefer a higher potency.
This supplement is a fantastic option for plant-based dieters seeking to maintain their B12 levels effectively.
- NATURAL ENERGY PRODUCTION - Vitamin B12 is known as the "energy vitamin" because it helps convert food into the energy that fuels your cells and metabolism
- MEMORY AND FOCUS - Vitamin B12 plays an important role in helping your nervous system function. Studies have shown it improves memory and focus, as well as your ability to learn
- ENHANCED WITH B COMPLEX VITAMINS - In addition to B12, Source of Life Garden Organic Vitamin B12 is enhanced with the other B Complex vitamins
- WHOLE FOOD BLEND - Each serving contains a certified organic whole food and herbal blend of blueberry, cranberry, blackberry, black currant, cherry, pomegranate, raspberry, broccoli, spinach, papaya, wild bilberry and kale
- ECO-FRIENDLY PACKAGING - Over 80,000 tons of packaging waste is generated in the U.S. every year; As part of an ongoing commitment to environmental preservation and protection, we’ve redesigned our packaging to eliminate the outer cardboard boxes
Conclusion
Choosing the best vitamin B12 supplement can significantly impact your overall health and wellness. In 2025, the market is teeming with options, making it essential for consumers to understand their needs and preferences. Whether you prefer tablets, sprays, or high-potency options, the above products cater to a variety of needs and budgets.
Do thorough research based on your dietary lifestyle, health goals, and preferences before making a final decision. Remember, it’s essential to consult with a healthcare provider before starting any new supplementation, especially if you have underlying health conditions or are taking other medications. By incorporating one of these high-quality B12 supplements into your regimen, you can help ensure that you meet your nutritional needs.
Last update on 2025-12-19 / Affiliate links / Images from Amazon Product Advertising API | hishecozy.com is a participant in the Amazon Associate program and will earn from qualifying purchases.
