Vaginal estrogen cream over the counter is becoming increasingly popular for many women looking for relief from symptoms associated with menopause. These products can provide significant benefits, including reduced vaginal dryness, improved sexual health, and more. The year is 2025, and we’ve scoured Amazon to find the best vaginal estrogen creams available for purchase. Below is a comprehensive guide to the top 10 products, including their benefits, features, and what makes them stand out in a saturated market.
A Buying Guide for Vaginal Estrogen Cream Over the Counter
When selecting a vaginal estrogen cream, it’s essential to consider various factors including formulation, active ingredients, user reviews, and price. Here’s a guide to help you make an informed decision:
Ingredients
Look for creams that contain natural or bioidentical estrogen, as these tend to replicate the body’s own hormones most effectively.
Concentration
Choose a cream with the right concentration of estrogen that meets your individual needs. Some products may be more concentrated than others.
Packaging
Opt for products with user-friendly packaging, such as tubes or applicators, that make it convenient to apply.
Brand Reputation
Consider the reputation of the brand and look for manufacturers that are known for quality.
Customer Reviews
Always check user reviews to gauge other women’s experiences with the product. This can provide insights into effectiveness and side effects.
Price
Find a product that fits your budget, but remember that the cheapest option isn’t always the best. Look for a balance between quality and cost.
Top 10 Vaginal Estrogen Creams Over the Counter from Amazon
1. Replens Long-Lasting Vaginal Moisturizer
Replens is a well-known brand that offers a long-lasting vaginal moisturizer. This product is hypoallergenic and is made without hormones, making it a great choice for women who are both hormonal and sensitive. Users often note its effectiveness in providing moisture and comfort.
- LONG-LASTING HYDRATION: This vaginal moisturizer rovides moisture for up to three days, offering lasting comfort and hydration
- SIMPLE APPLICATION: Comes with a reusable, mess-free vaginal applicator for an easy-to-use application experience, offering ease in maintaining vaginal moisture
- SUPPORTS NATURAL LUBRICATION: Supplements the body's natural vaginal lubrication and moisture to alleviate discomfort at the source
- DOCTOR-RECOMMENDED: Replens is the #1 Doctor-Recommended Vaginal Moisturizer Brand
- GENTLE & COMPATIBLE: Estrogen, and fragrance-free, Replens Moisturizer female internal vaginal applicators are formulated for regular use
2. Vagisil Prohydrate Supreme Vaginal Gel
Vagisil is widely recognized for its feminine care products. The Prohydrate Supreme Vaginal Gel contains natural ingredients that hydrate and soothe vaginal tissues, aiding in the relief of dryness. Its applicator is designed for easy use, making it a convenient option for many women.
- Vaginal moisturizer and personal lubricant for sex that feels like your own natural moisture
- Treats vaginal dryness by working with your body's natural lubrication
- No added perfumes, dyes, preservatives, or estrogen
- Does not interrupt the moment: Fast acting and long lasting formula that can be applied in advance of intimacy
- Bio-adherent vaginal lubricant for less mess
3. AZO Complete Feminine Balance Probiotics
Though not a cream, AZO offers probiotics that can complement the benefits of vaginal estrogen creams. These probiotics support healthy vaginal flora and pH balance. Many women find that combining probiotics with topical treatments provides comprehensive care.
- AZO COMPLETE FEMININE BALANCE: Maintaining vaginal PH balance might seem impossible in your fast-paced world but with AZO probiotics, we have your vaginal health needs covered from A to Z
- NATURALLY-SOURCED INGREDIENTS: AZO Complete Feminine Balance contains Intelliflora, a multi-strain probiotic blend that is clinically proven to work in 7 days
- SUGAR FREE AND GLUTEN FREE: Made with non-GMO ingredients with your nutritional health and wellbeing in mind
- HOW TO TAKE: Take one capsule of AZO Complete Feminine Balance once daily; vaginal probiotics restore a balanced PH. Safe to take during pregnancy
- CONVENIENT, EASY TO SWALLOW CAPSULES: Safe to take one capsule a day, any time of day with or without food
4. Soothe Vaginal Moisturizer
Soothe offers a vaginal moisturizer formulated without hormones and is specifically designed for women experiencing dryness. Its unique formula provides immediate and lasting relief, making it a favorite among users looking for quick comfort.
- HYDRATE & SOOTHE DAILY – Feel instant comfort with this hyaluronic acid vaginal moisturizer designed to combat everyday vaginal dryness. Made from water-based, gynecologist-tested ingredients, it provides hydration and soothing care for women of all life stages, making it a perfect for daily feminine care.
- NON-IRRITATING, SIMPLE FORMULA – Crafted without silicone, soy, estrogen, phytoestrogen, or added hormones, this vaginal cream is gentle and effective. Free from animal-derived ingredients, parabens, phthalates, sulfates, formaldehyde, and mineral oils, it offers clean, feminine care while being safe to use as a vaginal moisturizer.
- POWERED BY HYALURONIC ACID – This super humectant vaginal hyaluronic acid formula locks in moisture and improves elasticity. Naturally produced by your body, it helps restore hydration for smoother, more supple skin. This feminine lotion is perfect for your nether region needs and supports your intimate health with essential moisture.
- VERSATILE HYDRATION FOR DAY & NIGHT—For women experiencing perimenopause or menopause or daily dryness, Apply a pea-sized amount of this external vulva moisturizer. Gently massage into the vulva area for optimal comfort. Use it daily as a feminine lotion or labia moisturizer or to prepare for intimacy. It is for external use only, making it a safe and effective option.
- GYNECOLOGIST-TESTED & AWARD-WINNING – Recognized as a Health Editor's Pick 2023, this hyaluronic acid vaginal moisturizer is designed for your most intimate feminine care needs. With a fragrance-free, no-taste formula, it’s safe for use during intimacy and will not affect condom integrity. Suitable for everyday vaginal care and hydration.
5. Goodbye Glanditis Vaginal Cream
This unique product is formulated specifically for women suffering from vulvar dermatitis. It combines moisturizing properties with natural ingredients that support tissue health. Women praise this cream for being gentle and effective.
- Gentle Hydration for Lasting Comfort – Revita Vaginal Moisturizing Cream offers a hormone-free solution crafted to provide soothing hydration. Its natural blend of organic shea butter, cocoa butter, and sunflower oil delivers silky, long-lasting moisture that restores comfort and balance, making it an ideal choice for sensitive care. Use regularly to maintain hydration and wellness.
- Premium Ingredients for Natural Nourishment – This moisturizing cream combines the richness of almond oil, beeswax, and vitamin E with the deeply hydrating properties of hyaluronic acid. Together, these ingredients form a luxurious formula that enhances natural moisture, supports comfort, and promotes a smooth, rejuvenated feel without harsh chemicals or synthetic additives.
- Lightweight & Non-Greasy Formula – The lightweight, non-greasy texture of this cream absorbs effortlessly, leaving your skin feeling soft and moisturized without residue. Enriched with beeswax and natural oils, it delivers soothing hydration to delicate areas while maintaining a breathable finish. Perfect for daily or as-needed use to enhance your self-care routine.
- Convenient Pump Dispenser for Easy Application – Each container is designed with a precision pump dispenser, ensuring clean and consistent application every time. Three pumps deliver the perfect dose, minimizing waste and maximizing effectiveness. Incorporate this convenient feature into your regular routine for quick, mess-free moisturizing care.
- Crafted with Care in Certified Facilities – Revita Vaginal Moisturizing Cream is manufactured in a certified Kosher and registered facility, reflecting the highest standards of quality and care. Its hormone-free, natural formula ensures gentle hydration without compromising on safety. Store in a cool, dry place for optimal freshness and performance.
6. Herbalogy Vaginal Gel
Herbalogy offers a plant-based alternative to traditional estrogen creams. It is infused with natural herbal extracts known for their soothing properties. Users love this option for its natural smell and gentle formula that balances the vaginal region’s pH.
- Botanical Hydration for Women: Vagy Herbal Gels provide gentle, plant-based support for everyday intimate moisture, helping you feel fresh and cared for.
- Herbal Formula with Natural Extracts: Made with aloe, saffron, and traditional herbal ingredients, this vaginal gel is crafted for a soothing and smooth experience.
- Gentle and pH-Friendly: Designed with a focus on skin comfort, this product complements your body's natural balance and supports daily hygiene without harsh additives.
- Free from Irritating Additives: This natural moisturizer contains no synthetic hormones, parabens, or sulfates—just clean ingredients for personal lubrification.
- The package includes: A box with 5 vaginal gel ovules (3 g each), or a box of 10 ovules, suitable for continuous treatment for 5-10 days, making them ideal for regular intimate wellness routines.
7. Feminine Moisture Vaginal Cream by VMagic
VMagic is designed for daily use and is marketed as a natural product. This cream is formulated to relieve dryness while being free of parabens and other harsh chemicals. Reviews highlight its nourishing qualities and skin-friendly ingredients.
- OB/GYN-developed to keep the vulva and bikini area silky & smooth. For external use only.
- Fragrance-free and made for sensitive skin with organic coconut oil, cranberry seed oil, and beeswax.
- Perfect for razor burn, irritated skin, post-hair removal, and chafing.
- Has undergone third-party safety testing and ingredient purity testing, is made in FDA-registered and GMP-compliant facilities with traceable ingredients.
8. Nature’s Way Feminine Moisture Cream
Nature’s Way offers an all-natural vaginal moisturizer made from botanical extracts. Women appreciate this product for its lightweight texture and effectiveness, making it an ideal choice for daily use.
- Intimate Wellness Redefined: Experience lasting comfort with Arthcal pH-balancing formula specifically crafted for delicate feminine tissue. Helps maintain natural moisture levels while gently addressing dryness and discomfort associated with daily activities, hormonal changes.
- Soothing Relief for Sensitive Skin: Arthcal dermatologist-tested vaginal moisturizer creates a protective barrier against chafing and irritation. Enriched with against oxygen -rich botanical oils to nourish vulvar tissue, it helps reduce friction-related discomfort from exercise, clothing, or personal care routines.
- Nature-Infused Replenishment: Arthcal pH-balanced fusion of Grape Seed and Olive Oils mirrors skin’s natural moisture barrier, delivering silky hydration that won’t weigh you down. CoQ10 and Sea Buckthorn work in harmony to maintain private skin’s elasticity, with Coconut-derived emollients creating a breathable veil of long-lasting comfort.
- Gentle Care Commitment: Arthcal dermatologist-trusted blend features nourishing Beeswax and Shea Butter to lock in moisture without clogging pores. A soothing complex of Centella Asiatica with Chamomile and Baikal Skullcap root works to ease sensitivity, while Arthcal vegan formula excludes sulfates, parabens, and synthetic fragrances.
- Clinically Verified Comfort: Backed by user-validated results, 93% reported improved intimate comfort within 14 days of use, with 89% experiencing reduced irritation and 91% noticing visibly softer, smoother skin. Arthcal fast-absorbing formula delivers non-greasy hydration that lasts all day, making it ideal for daily wear—whether post-workout, during hormonal fluctuations, or as part of your regular self-care routine.
9. Ellen’s Essentials Organic Vaginal Moisturizer
This organic product is made from high-quality ingredients and is ideal for those seeking a more eco-friendly choice. Users appreciate that it’s free of chemicals, dyes, and artificial fragrances, focusing on gentle, natural care.
- Rejuvenate dry thinning vulvar tissue - All Natural & Organic vaginal cream helps rejuvenate and rehydrate vaginal dryness due to menopause, breastfeeding or other conditions. This feminine moisturizers organic ingredients help reduce irritation, itchiness, redness and burning of your most intimate areas
- Non Sticky - Smooth and oil based, this feminine moisturizer is formulated with your safety in mind as to not cause yeast infections or UTI's from use. Long lasting. Not latex compatible. Non GMO. Fragrance free.
- 100% All Natural & Certified Organic Ingredients Handmade in USA. Purified Water, Organic Extra Virgin Olive Oil, Beeswax with Pollen & Propolis, Vitamin E. No chemicals or fillers, no animal testing, no fragrances, no estrogen, no steroids, no dyes, no hormones, no synthetic preservatives, no petroleum, no parabens. Every ingredient is formulated to help restore your sensitive skin to its supple, youthful feminine best.
- USDA Certified Organic - Beeswax improves the elasticity, softness and suppleness of your skin. Propolis (contained within the Beeswax) helps the skin to heal & protects it from further damage. Bee pollen (contained within the Beeswax) is rich in many nutrients. Organic extra virgin olive oil has vitamin A & vitamin E & same fatty acids as your skin
- Formulated to deeply moisturize. No fillers or binders, so the vaginal cream is very concentrated. A little goes a long way towards menopause relief! Every ingredient has a beneficial effect on the skin. Leaves your skin well nourished & feeling hydrated & healthy. Fight off the free radicals. BeeFriendly makes the highest quality skin care products around!
10. Life-Flo Progesta-Care Vaginal Cream
Life-Flo offers a cream that contains natural progesterone, designed to provide symptomatic relief. Users report balanced hormonal feelings with this cream, leading to increased comfort.
- Emerita Tradition Since 1978 – Part of the Life-flo brand, Emerita Pro-Gest Balancing Cream is the original progesterone cream, designed for a woman's optimal balance. Each 1/4 teaspoon provides approximately 20 mg of USP progesterone from Mexican wild yam.
- Perfectly Balanced – Lightweight and fast-absorbing, our wild yam cream is formulated with soothing Aloe Vera, Safflower and Sweet Almond Oils to leave skin soft and hydrated.
- Easy to Apply – Dispense cream into the palm of your hand, then massage onto chest, abdomen, inner arms or thighs, rotating area each time. Apply once daily and use three weeks out of the month, then one week off.
- Trusted Quality – A leading brand of wellness products for women, Emerita by Life-flo offers a large selection of feminine hygiene products formulated with your health and comfort in mind.
- The Life-flo Difference – Fragrance free and made without parabens, our balancing cream is lab tested in our state-of-the-art facility in Utah to ensure the purity and potency of its ingredients. Like all Life-flo products, it comes with a 60-day money back guarantee and is not tested on animals.
Conclusion
Choosing the best vaginal estrogen cream over the counter can significantly impact your quality of life, especially if you’re dealing with menopause-related symptoms. Remember to consult with your healthcare provider before starting any new treatment, especially if you have existing health conditions or concerns.
With our list of the top 10 products—culled from user reviews and expert recommendations—you will be well-equipped to make an informed decision. Whether you’re looking for hormone-free moisturizers or creams that feature natural ingredients, there’s something on this list for everyone.
These creams provide significant benefits and can greatly enhance your comfort and quality of life. Get started on your journey to better feminine care today!
Last update on 2025-12-23 / Affiliate links / Images from Amazon Product Advertising API | hishecozy.com is a participant in the Amazon Associate program and will earn from qualifying purchases.
