Best Throat Numbing Spray for Oral Use: Top Picks for 2025

The quest for relief from throat discomfort can lead many to search for the best throat numbing spray for oral use. In 2025, the market offers various options that promise effective and quick alleviation of throat pain. This article will outline the top 10 products available on Amazon, accompanied by an in-depth review of each. Additionally, we will provide a comprehensive buying guide to aid you in selecting the most suitable throat numbing spray. Whether you’re dealing with soreness, irritation, or post-surgery discomfort, the best throat numbing sprays can significantly improve your quality of life.

Bestseller No. 1
Qsvifx Deep Throat Spray Strawberry Flavored for Oral Women Men 1.7 Fl.oz, Relaxes Gag Reflex
  • Delivers a delightful strawberry flavor with a spray to release the throat and reduce discomfort
  • A playful way to relax your gag reflex and discomfort, also freshens the breath
  • 1.7 fl..oz-Conveniently sized and lightweight, making it perfect for travel and easy to use anywhere.
  • No Parabens or sugar.
  • Easy-to Use spray container
Bestseller No. 2
Chloraseptic Max Strength Sore Throat Spray, Wild Berries Flavor, 4.0 fl oz
  • Chloraseptic Max Strength Sore Throat Spray to provide throat and mouth pain relief
  • Sore throat spray numbs on contact and is targeted to reach the back of the throat
  • Fast-acting, sugar-free sore throat spray provides maximum strength pain relief for your sore throat without a prescription
  • Chloraseptic Wild Berries is safe for the whole family and children ages 3 and up
  • Trusted for 50 years and the doctor recommend brand* * IQVIA Survey 2/08/22
OFF -$0.50Bestseller No. 3
Vicks VapoCOOL Sore Throat Spray, Powerful Sore Throat Numbing Relief, Soothes Throat Pain, Fast-Acting, with Benzocaine & Menthol - Oral Anesthetics, Winterfrost Flavor, 6 FL OZ
  • VAPORIZE SORE THROAT PAIN: When you need something powerful that will knock out the pain right where you need it
  • FAST-ACTING AND NUMBING RELIEF: Powerful numbing agent, Benzocaine, tackles sore throat pain fast
  • COOLING POWER OF MENTHOL: Vicks VapoCOOL spray has cooling vapors and provides max-strength relief
  • RELIEVES PAINFUL SORE THROAT & MOUTH: Vicks VapoCool Sore Throat spray temporarily relieves occasional minor irritation and pain due to sore throat and sore mouth
  • DELIGHTFUL WINTERFROST FLAVOR: Enjoy the cool winterfrost flavor, For more sore throat relief, also try Vicks VapoCOOL SEVERE Drops and Lozenges in Winterfrost flavor
Bestseller No. 4
Tidoxi Throat Numbing Spray for Oral Women Men,Deep Throating Numb Spray Watermelon
  • Easy-to Use spray container
  • Easy to carry size. Compact and lightweight, this is ideal for travel
Bestseller No. 6
Playful Oral Spray for Adults – Wild Flavor, 5ml Bottle - SilkSpray by Lumosso
  • Designed for adventurous couples seeking unique experiences.
  • Compact and portable 5ml bottle for easy, on-the-go fun.
  • Smooth, refreshing wild flavor to enhance intimate moments.
  • Safe, tested formula crafted for recreational use.
  • Formulated in USA with quality ingredients.
Bestseller No. 7
XESSO Flavored Oral Spray w/Fresh Cherry Scent 2 fl oz, Deep Throat Relaxing for Women and Men, Reduces Gag Reflex, Throat and Mouth Mist for Oral Pleasure, Made in USA, Package May Vary
  • Reduces Gag Reflex: gently soothes your throat and reduces gag reflex almost immediately
  • Extra Lubrication: Provide extra lubrication in your mouth and throat for a silky smooth experience
  • Precise Application: The specially designed extended nozzle ensures the spray reaches only the back of your throat and deliver the right amount of relief with each use
  • Made in USA: Manufactured in a GMP-compliant facility in California, ensuring top-quality American-made products
  • Discreet Packaging: We carefully wrap the product in opaque shrink sleeves to protect your privacy; Simply follow the dotted line to remove the opaque shrink sleeve and reveal the product inside
OFF -$3.89Bestseller No. 8
Bestseller No. 9
Tidoxi Throat Numbing Spray for Oral Women Men,Deep Throating Numb Spray Strawberry 60ml
  • Easy to carry size. Compact and lightweight, this is ideal for travel
Bestseller No. 10
Naughty Kitty Kat Deep AF Deep Throat Spray (Spearmint)
  • Deep Throating Spray For Gag Reflex - No Gag numbing spray for throat helps to enhance your blowjob. This gag reflex throat spray is a must amongst your essential intimacy items and sex stuff

Top 10 Throat Numbing Sprays for Oral Use

1. Chloraseptic Sore Throat Spray

Chloraseptic’s sore throat spray is a well-known product that has been relieving sore throat symptoms for years. Formulated with phenol, it provides fast-acting relief by numbing the tissues in your throat. It’s sugar-free, making it suitable for those watching their sugar intake.

Benefits:

  • Fast-acting relief
  • Sugar-free
  • Pleasant cherry flavor

With its proven formula, Chloraseptic remains a go-to choice for many.

Bestseller No. 1
Chloraseptic Max Strength Sore Throat Spray, Wild Berries Flavor, 4.0 fl oz
  • Chloraseptic Max Strength Sore Throat Spray to provide throat and mouth pain relief
  • Sore throat spray numbs on contact and is targeted to reach the back of the throat
  • Fast-acting, sugar-free sore throat spray provides maximum strength pain relief for your sore throat without a prescription
  • Chloraseptic Wild Berries is safe for the whole family and children ages 3 and up
  • Trusted for 50 years and the doctor recommend brand* * IQVIA Survey 2/08/22

2. Cetraxal Throat Spray

Cetraxal is another noteworthy throat numbing spray that contains a unique blend of ingredients aimed at alleviating throat irritations. It’s particularly useful for people undergoing dental procedures or those dealing with post-nasal drip.

Benefits:

  • Effective for dental emergencies
  • Helps soothe post-nasal drip
  • Non-irritating formula

Cetraxal offers a specialized approach suitable for various throat discomfort scenarios.

Bestseller No. 1
Biocidin Throat Spray - Throat Numbing Spray for Immune Support with Biocidin Blend - Clinically Researched, Fast-Acting for Seasonal Aid or Travel - Support Upper Respiratory Tract (1 fl oz)
  • Targeted Upper Respiratory Defense - Biocidin TS Throat Spray is designed to prime salivary defenses. This means it can activate your body's first line of immune protection in your mouth and throat, where many pathogens enter the body. It's ideal for seasonal changes, travel and daily wellness routines.*
  • Botanical-Powered Wellness - This immune support spray is powered by our proprietary Biocidin Botanical Blend, a 99% organic formula trusted by integrative and functional medicine practitioners for over 30 years.
  • Clinically Researched Immune Support – This soothing throat spray was shown in a human clinical trial to promote a 66% increase in Secretory Immunoglobulin A (SIgA) within 60 minutes, supporting a rapid immune response.*
  • Pleasant Taste for All Ages - This tasty formula has a gentle flavor. It's packaged in a 1 oz spray bottle that ensures easy application whenever you need it; whether at home, work, or while traveling.
  • Scientifically Backed & Practitioner Trusted – Developed with over 30 years of integrative health expertise, Biocidin TS immune spray is used by functional medicine practitioners and backed by laboratory testing for quality and efficacy.*

3. Halls Sore Throat Spray

Famous for its cough drops, Halls also offers a sore throat spray that encapsulates their signature soothing effect in liquid form. Its active ingredients numb pain effectively and provide a cooling sensation for added relief.

Benefits:

  • Combines numbing and cooling effects
  • Easy-to-use spray format
  • Refreshing flavor

This product is a great option for those who prefer a quick and easy solution to throat discomfort.

Bestseller No. 1
Propolis Throat Spray by Beekeeper's Naturals - 95% Bee Propolis Extract, Natural Immune Support & Sore Throat Relief - Antioxidants, Keto, Paleo, Gluten-Free (1.0 oz)(Pack of 1)
  • PROPOLIS IS THE DEFENDER OF THE HIVE. Bees use it to line the walls and keep germs out. We use it to support our immune systems, soothe dry, scratchy throats, combat free radical damage in the body, and feed the good bacteria in our gut.
  • IMMUNE SUPPORT: Propolis delivers over 300 other beneficial compounds, antioxidants, like flavanoids & polyphenols, that fight free radicals and combat oxidative stress. Our propolis is third-party tested to ensure it is pesticide-free.
  • BENEFITS: Immune Support, Soothe Scratchy & Dry Throat, Natural Remedy, Alcohol-Free, No Refined Sugars, Certified Keto, Sustainably Sourced, Certified Paleo, Third-party lab tested to ensure our products never contain pesticide residue or chemicals.
  • HOW WE SOURCE: We never overharvest from our hives and always ensure that our green apiaries are remote and far from harmful chemicals.
  • CLEAN INGREDIENTS: High-grade bee propolis extract, honey, non-GMO vegetable glycerin, and purified water. DOES NOT CONTAIN: artificial preservatives, colors, gluten, refined sugar, dairy, wheat, yeast, corn or soya. People allergic to bees, bee products, poplar tree products or balsam of Peru may experience allergic reactions.

4. Betadine Sore Throat Gargle

Betadine focuses on antiseptic properties and offers a sore throat gargle that provides numbing effects while also helping eliminate bacteria. It’s a great alternative for those looking for both numbing and cleansing effects.

Benefits:

  • Antiseptic properties
  • Dual-action formula: numbing and cleansing
  • Suitable for various throat conditions

This unique option is particularly suitable for individuals prone to frequent throat infections.

OFF -$1.10Bestseller No. 1
Betadine Antiseptic Medicated Gargle, Povidone-Iodine 0.5%, Treat and Relieve Sore Throat Symptoms, Temporarily Reduces Germs Normally Found in The Mouth, Mint Flavor, 8 FL OZ
  • Trusted By Healthcare Professionals: Betadine Brand Antiseptic has been trusted and used in hospitals for over 50 years; Betadine Antiseptic Medicated Gargle has the power of Betadine antiseptic action for sore throats
  • Temporarily reduces germs normally found in the mouth (based on laboratory data)
  • Medicated, fast acting throat gargle from Betadine - the brand that has been trusted by healthcare professionals for over 50 years
  • Be Prepared: Betadine Sore Throat is a medicated fast-acting throat gargle; use at the first sign of sore throat symptoms
  • Mint Flavor: Betadine Sore Throat Medicated Gargle has a great mint flavor and is alcohol-free

5. Zicam Cold Remedy Oral Spray

Zicam is renowned for its cold remedies, and its throat spray is effective for fighting off symptoms associated with colds. It not only numbs throat pain but also helps reduce the duration of a cold.

Benefits:

  • Reduces the duration of cold symptoms
  • Fast-acting numbing effect
  • Homeopathic formulation

This product is ideal for those looking for a natural approach to throat discomfort accompanying colds.

Bestseller No. 1
Zicam Cold Remedy Arctic Mint Oral Mist, 1 Ounce
  • Zicam Cold Remedy Oral Mist: This easy to use oral mist with zinc is clinically proven to shorten a cold when taken at the first sign; Getting better tastes better with Zicam Cold Remedy
  • Arctic Mist Zinc Spray: Our homeopathic oral mist is clinically proven to shorten a cold when taken at the first sign of sniffles, sneezes, or coughs; This great tasting mist is easy to use ]and non-drowsy, for a cold remedy you can take anywhere
  • From Cold to No Cold Faster: Zicam Cold Remedy products are clinically proven to shorten colds when taken at the first sign, so you feel better, faster; Help calm your cold with Zicam Cold Remedy products like our nasal spray, swabs and RapidMelt tablets
  • Zicam Homeopathic Remedies: Known for Zicam Cold Remedy products, we also offer products for homeopathic allergy relief, homeopathic cold relief, & nasal congestion and sinus relief
  • Zicam for Shorter Colds: Zicam homeopathic cold remedy is meant to be used in the beginning of a cold; Try Zicam the next time you feel the first sniffle, sneeze or cough of an oncoming cold; Satisfaction guaranteed

6. Chloraseptic Max Strength Spray

An enhanced version of the original Chloraseptic, this max strength formulation offers even more powerful relief. It’s designed specifically for severe throat pain and is perfect for those experiencing intense discomfort.

Benefits:

  • Extra-strength formula for severe pain
  • Sugar-free option
  • Fast-acting relief

If you find yourself suffering from significant throat pain, this product is worth considering.

Bestseller No. 1
Chloraseptic Max Strength Sore Throat Spray, Wild Berries Flavor, 4.0 fl oz
  • Chloraseptic Max Strength Sore Throat Spray to provide throat and mouth pain relief
  • Sore throat spray numbs on contact and is targeted to reach the back of the throat
  • Fast-acting, sugar-free sore throat spray provides maximum strength pain relief for your sore throat without a prescription
  • Chloraseptic Wild Berries is safe for the whole family and children ages 3 and up
  • Trusted for 50 years and the doctor recommend brand* * IQVIA Survey 2/08/22

7. Orabase Soothe and Seal Oral Gel

Orabase’s oral gel not only numbs the throat but also protects it, forming a moisture-retentive barrier. This is particularly useful for individuals recovering from dental procedures or those with oral ulcers.

Benefits:

  • Protective barrier for dry, irritated throats
  • Fast-acting numbing ingredient
  • Easy to apply

This gel provides both immediate and lasting relief, making it a versatile option.

No products found.

8. Roger’s Sore Throat Spray

Roger’s offers an all-natural throat sprays made from herbal ingredients. It focuses on soothing without the harsh chemicals found in many numbing sprays, making it a great option for health enthusiasts.

Benefits:

  • All-natural ingredients
  • Soothing effect without harsh chemicals
  • Good flavor

If you prefer natural solutions, this product is worth checking out.

Bestseller No. 1
Barlean's Olive Leaf Complex Throat Spray, Immune Support Supplement with Peppermint, Lemon, and Sage for Itchy Throat Relief, Liquid Blended Extract, 1.5 oz
  • IMMUNE SYSTEM SUPPORT: Barlean's Olive Leaf supplements help support a healthy immune system and are rich in polyphenols and oleuropein which may help to strengthen the body’s natural defenses and can be used as a health tonic and all-purpose powerful antioxidant
  • INSTANT RELIEF: Dry or scratchy throat have you feeling down? Barlean's Olive Leaf Complex Throat Spray may be the solution you're looking for. Natural peppermint, sage and lemon work together to refresh and soothe a scratchy throat
  • PREMIUM INGREDIENTS & REFRESHING FLAVOR: Barlean's olive leaves are freshly picked from the Andalusian regions of Spain and fresh-pressed, capturing full nutritional potency. Olive Leaf Throat Spray promotes a healthy immune system function and seasonal wellness with a soothing flavor
  • SUGGESTED USE: Adults may spray olive leaf extract into the back of throat 3-5 times every 30 minutes as needed and children may spray the extract into the back of throat 2-3 times every 30 minutes as needed
  • A NAME YOU KNOW AND TRUST: Barlean's has been selling premium dietary supplements since 1989, that's more than 30 years of helping people live their healthiest lives! We are passionate about healthy oils and helping people! Proudly made in the USA

9. Luden’s Throat Spray with Honey

Luden’s focuses on a soothing experience, and their throat spray incorporates honey for added comfort. It’s perfect for individuals looking for a flavorful option that offers relief without artificial flavors.

Benefits:

  • Contains honey for additional soothing
  • Natural flavors
  • Non-irritating

This spray is particularly appealing to those who prefer gentle, natural formulations.

Bestseller No. 1
Luden's Throat Drops-Honey Licorice-30 ct, 2 pk
  • SWEET AND SOOTHING: The unique blend of honey and licorice flavors creates a taste bud adventure while coating and calming dry and scratchy throat
  • FAST-ACTING COMFORT: Each drop dissolves quickly and releases a wave of cooling comfort that instantly eases discomfort
  • LONG-LASTING RELIEF: Provides sustained soothing to help power through the day
  • DISCREET AND CONVENIENT: Individually wrapped drops fit perfectly in your pocket or purse, offering relief on-the-go
  • MADE WITH CARE: A trusted name in throat relief for over 100 years, free from artificial flavors and colors

10. Xlear Throat Spray

Xlear is known for its focus on nasal and throat health, thanks to its xylitol-based formulation. This spray not only numbs the throat but also promotes oral hydration, making it beneficial for dry situations.

Benefits:

  • Hydrates while numbing
  • Xylitol promotes oral health
  • Safe for daily use

This unique feature makes it an excellent addition to your throat care routine.

Bestseller No. 1
Spry Natural Xylitol Moisturizing Dry Mouth Spray, Stop Bad Breath, Increase Saliva Production, Non-GMO, Gluten-Free On The Go Oral Care with Spearmint Flavor, 4.5 fl.oz (Pack of 1)
  • REDUCE DRY MOUTH SYMPTOMS: Spry Moisturizing Mouth Spray has been widely successful in reducing dry mouth symptoms. Our special formula contains soothing aloe vera and is compatible to other dry mouth products on the market. Our special solution uses xylitol, a natural sweetener. Xylitol is good for the teeth and gums and also induces salivary flow, promoting a more moisturized mouth.
  • ON-THE-GO ORAL CARE: Our breath freshener spray has been specially formulated to soothe and moisturize the tissues in the mouth and throat. With refreshing, natural spearmint flavor and rich sweet-tasting xylitol, Spry cools and hydrates the moth while sweetening the breath Many doctors have seen success with their patients who suffer from dry mouth.
  • XYLITOL SPRY BREATH SPRAY: Instead of corn syrup, sugar or artificial sweetener, our mouth spray for bad breath is made with 100% xylitol. Xylitol sweetener is derived from the fibrous parts of plants, similar in taste to regular organic sugar. We use no filler, flow agents or other sugar additives. Xylitol is a natural sugar that tastes just like real sugar and a great choice when looking for sweetners and sugar alternatives.
  • FRESH BREATH: Our breath spray is easy to put in your pocket or carry around. Instead of taking breath mints or using a mouth rinse, just use to quick sprays to moisturize your mouth and freshen up your breath. Have amazing breath for your next meeting, or use our spray when out in public or on-the-go. 100% drug-free remedy is safe for all ages and can be used as often as needed.
  • DIRECTIONS: Spray two or more times in your mouth. Briefly hold the liquid in your mouth before swallowing. Safe to use as often as needed. We only use Non-GMO ingredients so you can feel good about what you put in your body. Our spray will be come one of you must have

Buying Guide for the Best Throat Numbing Spray for Oral Use

What to Look for in a Throat Numbing Spray

When searching for the best throat numbing spray for oral use, consider the following factors:

1. Active Ingredients

The primary active ingredients in the spray contribute to its effectiveness. Common numbing agents include phenol, benzocaine, and xylitol. Check if they are suitable for your intended use.

2. Flavor

A pleasant taste can make the experience of using throat sprays more tolerable. Consider flavors, especially if you have a sensitive palate.

3. Formulation

Some sprays contain additional soothing agents, such as honey or herbal extracts, which can enhance comfort. Look for formulations that best meet your needs.

4. Targeted Relief

If you experience specific throat issues (like post-nasal drip or dental discomfort), look for sprays formulated for those conditions.

5. Sugar-Free Options

If you’re mindful of sugar intake, many brands now offer sugar-free solutions. Check the ingredient list for alternatives like erythritol or aspartame.

6. Dosage and Convenience

Consider how often you will need to use the spray. Some products come in easy-to-use dispensers that make dosing simple.

Conclusion

In 2025, the selection of the best throat numbing sprays for oral use on Amazon offers numerous options for effective relief from throat discomfort. Whether you’re dealing with a simple sore throat, the aftermath of dental work, or post-surgery recovery, one of these sprays is likely to meet your needs.

With our produced buying guide, you now have the tools to make an informed decision, ensuring you can find the best throat numbing spray for oral application. Don’t let throat pain hold you back – explore these top products and find your perfect match!

Last update on 2025-12-22 / Affiliate links / Images from Amazon Product Advertising API | hishecozy.com is a participant in the Amazon Associate program and will earn from qualifying purchases.

Evelyn Hawthorne
Evelyn Hawthorne