When it comes to maintaining optimal health, Vitamin B12 stands out as an essential nutrient. Known for its important role in energy production, red blood cell formation, and neurological function, it’s crucial to find a high-quality B12 supplement. If you’re searching for the best B12 supplements on Amazon, you’re in luck! This article dives into the top 10 products available, along with a buying guide to help you make the best choice for your health.
Bestseller No. 1
Nature Made Vitamin B12 1000 mcg, Dietary Supplement for Energy Metabolism Support, B12 Vitamins 1000 mcg, 150 Softgels, 150 Day Supply
- Energy metabolism support supplement(1): contains one 150 count bottle of Nature Made Vitamin B12 1000 mcg Softgels for a 150 day supply
- These Nature Made B12 1000mcg softgels help break down food into energy that your body can use all day long
- Vitamin B 12 helps support brain cell function and mood health (2)
- Vitamin B12 is important for proper red blood cell formation and helps reduce fatigue for those low in B12 vitamins
- Adults take one B 12 vitamin softgel daily with water and a meal
Bestseller No. 2
EZ Melts Dissolvable B12 2,500 mcg - Vitamin B12 for Energy & Immune Support - Non-GMO, Vegan & Gluten-Free - Red Cherry - 90 Sublingual Tablets (90 Servings)
- Vitamin B12 Supplement: EZ Melts B12 are dissolvable tablets that deliver 2,500 mcg of vitamin B12 per serving for easy metabolic energy support*
- Energy Support Supplement: Supports healthy energy levels, cellular health, and natural energy production to support overall wellness*
- Brain Health Supplement: Methylcobalamin B12 is essential to help maintain focus and cognitive function, so you can stay alert when it matters most*
- Mood Support Supplement: Supports nervous system function, which helps maintain clarity*
- Non-GMO & Vegan Supplement: EZ Melts makes it easier to take superior quality vitamins—free from artificial flavors, gluten, dairy, soy, and sugar
Bestseller No. 3
Nature Made Maximum Strength Vitamin B12 5000 mcg, Dietary Supplement for Energy Metabolism Support, 60 Softgels, 60 Day Supply
- Energy metabolism support supplement(1): contains one 60 count bottle of Nature Made Maximum Strength Vitamin B 12 5000 mcg Softgels for a 60-day supply
- Vitamin B12 supplements help break down food into energy that your body can use all day long
- Nature Made B12 Vitamins 5000 mcg helps support brain cell function and mood health(3)
- Vitamin B12 is important for proper red blood cell formation and helps reduce fatigue for those low in B12 vitamins
- Adults, take one Vitamin B-12 softgel daily with water and a meal
Bestseller No. 4
Nature's Bounty Vitamin B12 1000 mcg Supplements, Supports Energy Metabolism, 200 Ct
- SUPPORTS CELLULAR ENERGY HEALTH (1): Nature's Bounty Vitamin B-12 1000 mcg aids in converting food into cellular energy (1)
- CARDIOVASCULAR SUPPORT (1): Vitamin B-12 supplements contribute to the health of your cardiovascular and circulatory systems (1)
- MAINTAINS HEALTHY NERVES (1): Great for nerve health, B-12 vitamin helps maintain healthy nerve cells (1)
- EASY TO SWALLOW: These Vitamin B-12 tablets are coated so they are easy to swallow, providing convenience in your daily vitamin regimen
- TRUSTED WELLNESS: From trusted wellness experts, these B-12 Vitamins are made with quality ingredients, backed by 50 years of scientific research
Bestseller No. 5
THORNE - Vitamin B12 - as Methylcobalamin - Supports Heart & Nerve Health, Blood Cell Function, Restful Sleep & Methylation* - Third-Party Certified - Gluten, Dairy & Soy-Free - 60 Capsules
- Active B12: Each capsule provides 1 mg vitamin B12 as methylcobalamin, which is more efficiently used by the body compared to other forms of vitamin B12, like cyanocobalamin
- Heart & Brain Health: Supports a normal level of homocysteine in the body to benefit healthy cardiac function, blood cell formation, and optimal nerve function*
- Sleep Support: Helps maintain normal circadian rhythms to support restful sleep and supports healthy methylation processes in the body*
- Third-Party Certified: This product has been third-party tested and certified to verify what's in the package matches what's on the label and to confirm it contains no unsafe levels of contaminants
- Trusted: Thorne is chosen by champions and trusted by 100+ professional sports teams, a proud partner of U.S. National Teams, and the #1 recommended clinical brand by health-care practitioners (2023 Health-Care Practitioner Seller Survey)
Bestseller No. 6
Nature’s Bounty Vitamin B12 5000 mcg Sublingual Liquid, Cardiovascular Health & Cellular Energy Support, 2 Fl Oz (1 Count)
- CELLULAR ENERGY SUPPORT (1) Nature’s Bounty Vitamin B-12 Sublingual Liquid plays an important role in energy metabolism (1); it helps the body convert food into cellular energy your body needs (1)
- SUPPORTS HEART HEALTH (1) Nature’s Bounty Vitamin B-12 is commonly used to support the health of the cardiovascular and circulatory systems (1); Vitamin B-12 is also an important vitamin for maintaining healthy nerve cells (1)
- EASY-TO-TAKE LIQUID Nature’s Bounty Vitamin B-12 Sublingual Liquid makes it easy to get your daily dose of this essential nutrient; Simply place 1 mL daily under the tongue and hold there for 30 seconds before swallowing; You’ll love the delicious, natural berry flavor
- QUALITY IS OUR PRIORITY Nature’s Bounty is committed to the safety of all of our supplements; Our Vitamin B-12 liquid is gluten free; sugar free; contains no artificial colors or flavors; and is suitable for vegetarians
- FROM THE TRUSTED WELLNESS EXPERTS Nature’s Bounty Vitamin B-12 Sublingual Liquid is a product of nearly 50 years of dedication to quality; consistency and scientific research to make vitamins and nutritional supplements of unrivaled excellence
Bestseller No. 7
Doctor's Best Fully Active B12 1500 mcg, Non-GMO, Vegan, Gluten Free, Supports Healthy Memory, Mood and Circulation, 60 Count
- VITAMIN B12 SUPPLEMENT: This fully active, methylated B12 (as methylcobalamin) provides essential support for energy production, red blood cell production, and overall wellness in men and women
- ENERGY AND MEMORY SUPPORT: Methylcobalamin promotes brain health, memory, and mental clarity, helping maintain focus and energy during busy and demanding days
- BETTER ABSORPTION: This methyl form of B12 is bioactive and designed for superior absorption. As the active form of Vitamin B12, it can be directly used by the body without needing further conversion
- 1500 MCG PER SERVING: Each vegetarian capsule delivers 1500 mcg of methylated B12 and is non-GMO, vegan, gluten free, and soy free for convenient daily nutrient support
- DOCTOR'S BEST: Good nutrition starts with sound science. For over 35 years, we have been dedicated to providing only thoroughly researched, rigorously tested, and clinically-approved supplements
Bestseller No. 8
Pure Encapsulations B12 Folate - Energy Supplement to Support Nerves, Energy Metabolism & Cognitive Support* - with Vitamin B Folate as Metafolin - 60 Capsules
- Premium Folate Supplement: Vitamin B12 and folate help convert carbohydrates into energy and break down proteins in the body; provides metabolism support*
- Nervous System Support: Vitamin B12 (methylcobalamin) and folate (L-5-MTHF) support the nervous system, and function as hair, skin, and liver aids.*
- Cognitive Support: Folate is essential for fetal neural development; B12 is an important nutrient for memory and cognitive support*
- Supports Gut Health: Support G.I. tract thanks to the active form of the B12 vitamin, methylcobalamin; also a liver support supplement*
- Pure Difference: What we leave out matters, too; Pure Encapsulations products are free from common allergens, artificial or unnecessary ingredients, and GMOs
Bestseller No. 9
Jarrow Formulas Methyl Vitamin B12 5000 mcg - 60 Chewable Tablets, Naturally Fruit Flavored- Bioactive B12 Vitamin - Supports Cellular Energy Production, Brain Health & Metabolism - 60 Servings
- Bioactive B12: Jarrow Formulas Methyl B-12 (methylcobalamin) is the biologically active form of vitamin B12; supports brain and nerve health, cellular energy production, healthy cell replication, and red blood cell production (1)
- Homocysteine Metabolism: Methyl B-12 is required for the normal metabolism of homocysteine, supporting its conversion to methionine
- Better Retained With Jarrow B12: Research suggests that methyl B-12 is better retained in the body than cyanocobalamin, and supplementation may be needed by some vegetarians and vegans (1)
- Convenient Chewable Tablet: Each lemon flavored chewable tablet delivers 1000 micrograms (mcg) of methyl B-12; our B12 methylcobalamin formula does not contain wheat, gluten, soybeans, dairy, egg, fish, shellfish, or peanuts, tree nuts or sesame
- Superior Nutrition & Formulation: The goal of Jarrow Formulas is to promote optimal health with effective, affordable, and superior formulation of dietary vitamins and supplements; our customers can be assured of purity, value & potency
Bestseller No. 10
Nature Made Vitamin B12 1000 mcg, Easy to Take Vitamin B12 Sublingual Tablets for Energy Metabolism Support, 150 Sugar Free Fast Dissolve Tablets, 150 Day Supply
- Energy metabolism support supplement(1): contains one 150 count bottle of Nature Made Sublingual B12 1000 mcg Fast Dissolve Tablets for a 150-day supply
- Nature Made B12 1000mcg tablets help break down food into energy that your body can use all day long
- B-12 vitamin helps support brain cell function and mood health(2)
- Vitamin B12 supplements provide B12, which is important for proper red blood cell formation and helps reduce fatigue for those low in B12 vitamins
- Easy to take with a great tasting flavor; simply dissolve one B12 1000 mcg sublingual tablet under tongue before swallowing. Adults take one Vitamin B12 tablet daily with a meal
Buying Guide: How to Choose the Best B12 Supplement
Selecting the best B12 supplement can be overwhelming given the vast options available. Here’s a brief guide to help you make an informed decision:
1. Forms of B12
- Methylcobalamin: This is the most bioactive form and often recommended for its superior absorption and efficacy.
- Cyanocobalamin: While this synthetic form is stable and widely used, it must be converted into an active form by your body.
- Other Forms: B12 is also available as adenosylcobalamin and hydroxocobalamin, which are beneficial in various contexts.
2. Dosage
- Typical dosages range from 500 mcg to 5000 mcg. Your needs may vary based on dietary restrictions, lifestyle, and health conditions.
3. Additional Ingredients
- Some supplements come with added nutrients like folic acid, Vitamin D, or herbal extracts, which can amplify the health benefits.
4. Delivery Method
- B12 supplements come in various forms, including tablets, sublingual lozenges, sprays, and gummies. Choose one that fits your preference.
5. Quality and Brand Reputation
- Look for products that are third-party tested for quality and free from harmful additives.
6. Vegetarian or Vegan Options
- If you’re following a plant-based diet, make sure to choose B12 sourced from non-animal origins.
With these points in mind, let’s delve into the best B12 supplements available on Amazon in 2025.
Top 10 B12 Supplements on Amazon
1. Nature Made Vitamin B12 1000 mcg
Nature Made offers a reputable B12 supplement that is free from gluten and artificial colors. Each tablet provides 1000 mcg of cyanocobalamin, making it suitable for most adults.
This product is known for its high absorption rate, but it may require a doctor’s approval for those with certain medical conditions.
Bestseller No. 1
Nature Made Vitamin B12 1000 mcg, Dietary Supplement for Energy Metabolism Support, B12 Vitamins 1000 mcg, 150 Softgels, 150 Day Supply
- Energy metabolism support supplement(1): contains one 150 count bottle of Nature Made Vitamin B12 1000 mcg Softgels for a 150 day supply
- These Nature Made B12 1000mcg softgels help break down food into energy that your body can use all day long
- Vitamin B 12 helps support brain cell function and mood health (2)
- Vitamin B12 is important for proper red blood cell formation and helps reduce fatigue for those low in B12 vitamins
- Adults take one B 12 vitamin softgel daily with water and a meal
2. Garden of Life mykind Organic B12 Spray
Formulated in a convenient spray form, this organic B12 supplement uses methylcobalamin for better absorption and is free from artificial additives.
It’s also certified USDA organic, making it a great choice for health-conscious consumers. The spray is easy to use and has a pleasant taste, though the size may be less familiar for some.
Bestseller No. 1
Garden of Life Organics B-12 Spray with Methylcobalamin – Liquid Vitamin Spray for Energy, Metabolism & Heart Health Support, Raspberry Flavor, 2 Fl Oz Bottle, 140 Servings
- B12 VITAMIN SPRAY: One serving of 2 oz delivers 500mcg vegan methylcobalamin (8333% DV) B12 to support energy metabolism and heart health*
- B12 VITAMIN LIQUID FORMULA: Garden of Life liquid vitamin features 500mcg methylcobalamin—the active form of vitamin B12 found in your body for maximum effectiveness
- HEART HEALTH & METABOLISM: This vitamin B12 spray supports energy metabolism, heart health, and a healthy central nervous system*
- CLEAN & CERTIFIED: USDA Organic, Non-GMO Project Verified, Vegan, Gluten-Free, Kosher, no artificial colors or preservatives
- EASY DAILY SUPPORT: Take 1 convenient spray daily and swallow; delicious raspberry flavored vitamin spray delivers concentrated B12 for energy metabolism support throughout the day*
3. Solgar Vitamin B12 1000 mcg Nuggets
Solgar’s B12 nuggets utilize methylcobalamin to support energy production and overall well-being. The nuggets dissolve quickly under the tongue, contributing to rapid absorption.
This brand is well-regarded for its commitment to quality, although its larger nugget size might be a minor inconvenience for some.
Bestseller No. 1
Solgar Vitamin B12 1000 mcg, 250 Nuggets - Supports Production of Energy, Red Blood Cells - Healthy Nervous System - Promotes Cardiovascular Health - Vitamin B - Non-GMO, Gluten Free - 250 Servings
- Energy Support; Vitamin B12 is part of a group of essential nutrients known as the B Complex; It supports energy metabolism and promotes a healthy nervous system
- Supports Heart Health; B12 supports heart health by promoting healthy levels of homocysteine already within a normal range; It also assists in the regeneration of red blood cells, which help to deliver oxygen throughout the body
- Convenient Dosage; Solgar Sublingual 1000 mcg Vitamin B12 nuggets melt under the tongue for fast, easy absorption
- Non-GMO, Kosher & Gluten Free; Solgar Vitamin B12 nuggets are suitable for vegans; Free of: gluten, wheat, dairy, soy, yeast, sugar, sodium, artificial flavor and color
- The Gold Standard: For over 70 years, Solgar has been committed to quality, health, and well-being. Our mission is to create the finest nutritional supplements in small batches, through tireless research, using only the finest raw materials
4. NOW Foods B-12 5000 mcg
For those needing higher doses, NOW Foods B-12 provides each serving with an impressive 5000 mcg of methylcobalamin.
This option is especially suitable for individuals who may be deficient due to lifestyle or dietary habits. However, those new to B12 may want to start with a lower dosage.
Bestseller No. 1
NOW Foods Supplements, Methyl B-12 (Methylcobalamin) 5,000 mcg, Nervous System Health*, 120 Lozenges
- ESSENTIAL FOR ENERGY PRODUCTION*: Vitamin B-12 is necessary for the production of energy from fats and proteins and is well known for its critical role in DNA synthesis, as well as in homocysteine metabolism*
- METHYLCOBALAMIN PLUS FOLIC ACID: Methyl B-12 is vegetarian/vegan (non-animal derived)
- CERTIFICATIONS/CLASSIFICATIONS: Kosher, Soy Free, Vegan
- GMP Quality Assured: A-rated, third-party certification means that every aspect of the NOW manufacturing process has been examined. Our in-house laboratories are ISO/IEC accredited for laboratory testing including for stability, potency and product formulation.
- Founded in 1968 by Elwood Richard, NOW is one of the largest independent, family- and employee-owned manufacturers of natural products
5. Jarrow Formulas Methyl B-12 1000 mcg
Jarrow’s formulation features high-potency methylcobalamin designed for fast sublingual absorption. This product is ideal for vegans and vegetarians and is free from common allergens.
The taste is more pleasant compared to traditional B12 tablets but may be more suited for individuals familiar with sublingual supplements.
Bestseller No. 1
Jarrow Formulas Methyl Vitamin B-12 1000 mcg, 100 Chewable Tablets, Lemon Flavored- Bioactive B12 Vitamin - Supports Cellular Energy Production, Brain Health & Metabolism - 100 Servings
- Bioactive B12: Jarrow Formulas Methyl B-12 (methylcobalamin) is the biologically active form of vitamin B12; supports brain and nerve health, cellular energy production, healthy cell replication, and red blood cell production (1)
- Homocysteine Metabolism: Methyl B-12 is required for the normal metabolism of homocysteine, supporting its conversion to methionine
- Better Retained With Jarrow B12: Research suggests that methyl B-12 is better retained in the body than cyanocobalamin, and supplementation may be needed by some vegetarians and vegans (1)
- Convenient Chewable Tablet: Each lemon flavored chewable tablet delivers 1000 micrograms (mcg) of methyl B-12; our B12 methylcobalamin formula does not contain wheat, gluten, soybeans, dairy, egg, fish, shellfish, or peanuts, tree nuts or sesame
- Superior Nutrition & Formulation: The goal of Jarrow Formulas is to promote optimal health with effective, affordable, and superior formulation of dietary vitamins and supplements; our customers can be assured of purity, value & potency
6. MaryRuth Organics Liquid B12
Liquid B12 is a great alternative for those who have difficulty swallowing pills. This vegan-friendly option is made with methylcobalamin and is sweetened using organic cane sugar.
While the taste is quite good, dosing may require more care compared to traditional capsules.
Bestseller No. 1
MARYRUTH'S Organic Methyl B12 Spray | 1,500 mcg B12 Per Serving | Methylcobalamin | Energy Metabolism | Cognitive Function | Neuro Health | Vegan | Gluten Free | Sugar Free | 1 Fl Oz
- Bioavailable B12: Many B12 supplements use cyanocobalamin, a synthetic form of B12 that contains cyanide. Ours is formulated with methylcobalamin, which has superior bioavailability to cyanocobalamin and is a preferred form for some with MTHFR gene variants!
- Multiple Benefits: Vitamin B12 supports energy metabolism as well as cognitive function, nervous system function, and neuro health to give you the targeted and convenient support you need on your busy days.Multiple Benefits: Vitamin B12 supports energy metabolism as well as cognitive function, nervous system function, and neuro health to give you the targeted and convenient support you need on your busy days.
- Cellular Health: This essential vitamin plays a key role in supporting cellular health in addition to red blood cell production. Plus, B12 supports DNA synthesis, supporting your overall wellness.
- Easy-to-Take Spray: No more hard-to-swallow pills or capsules! With 1,500 mcg per serving, this organic berry-flavored spray offers a simple, portable way to support your overall wellness with just 2 sprays daily!
- For Most Lifestyles: MaryRuth's Methyl B12 Spray is USDA Organic, Vegan, Non-GMO, Dairy Free, Nut Free, Gluten Free, Soy Free, Sugar Free, Made in a GMP Facility. Clean Label Project Certified. B Corp Certified. Women Owned Business.
7. Clinical Effects B12
Clinical Effects offers a potent vegan B12 supplement with 3000 mcg of methylcobalamin per serving.
The product comes in a spray form, making it convenient and easy to use. However, some users may find the flavor to be on the artificial side.
Bestseller No. 1
BioActive Vitamin B Complex - Blood Stream Ready, Methylated B Complex - Featuring Methylfolate, 3 BioActive Forms of B12, BenfoPure® B1 & Pantesin® B5 - 12 B Vitamins in Clinical Doses - 60 Servings
- ACTIVE & METHYLATED FORMS FOR MAX ABSORPTION: Each B vitamin is delivered in its bloodstream-ready, active or methylated form—no extra processing required. This means faster, more effective results for energy, metabolism, and overall vitality.*
- FULL-SPECTRUM, BIOACTIVE FORMS OF B12 COMPLEX: Features Methyl B12, Adenosyl B12, and Hydroxo B12 to ensure both immediate and long-lasting B12 availability, optimizing cellular energy production and detox support.*
- L-METHYLFOLATE (5-MTHF) FOR SUPERIOR FOLATE SUPPORT: Utilizes the most bioactive form of B9 to enhance cognitive function, support healthy mood, and maintain proper homocysteine levels, especially vital for those with methylation difficulties.*
- PREMIUM BenfoPure® B1 & Pantesin® B5 FOR BETTER PERFORMANCE: BenfoPure® Benfotiamine (B1) and Pantesin® Pantethine (B5) deliver up to 500% more effectiveness than standard forms, fueling heart health, nerve function, and efficient metabolism.*
- B complex vitamins for Overall Wellness: Enjoy comprehensive benefits—from helping support healthy energy levels, cognitive function, and mood balance to promoting heart health, a normal stress response, a healthy metabolism, and vibrant hair, skin, and nails—all through the highly bioavailable, fully active, methylated B vitamins.*
8. Nutricost Vitamin B12 5000 mcg
Nutricost provides a high-dose B12 supplement in an easy-to-swallow capsule form, making it preferable for those who dislike sprays or lozenges.
This product is gluten-free and non-GMO, although potential buyers should note that it contains gelatin.
Bestseller No. 1
Nutricost Vitamin B12 (Methylcobalamin) 5000mcg, 240 Capsules - Vegetarian Caps, Non-GMO, Gluten Free B12 Supplement
- 5000mcg (5mg) of Vitamin B12 Per Serving
- 240 Servings Per Bottle, 1 Capsule is 1 Serving
- Vegetarian, Non-GMO & Gluten Free
- Each Batch is Tested by Independent, ISO-Accredited Laboratories
- Made in an NSF Certified, GMP Compliant, FDA Registered Facility.
9. EZ Melts B12 1000 mcg
EZ Melts delivers a unique twist with its melt-in-your-mouth technology, making it easy to absorb while enjoying delicious flavors.
It’s suitable for both vegetarians and vegans, though the price point might be higher compared to traditional pills.
Bestseller No. 1
EZ Melts Dissolvable B12 2,500 mcg - Vitamin B12 for Energy & Immune Support - Non-GMO, Vegan & Gluten-Free - Red Cherry - 90 Sublingual Tablets (90 Servings)
- Vitamin B12 Supplement: EZ Melts B12 are dissolvable tablets that deliver 2,500 mcg of vitamin B12 per serving for easy metabolic energy support*
- Energy Support Supplement: Supports healthy energy levels, cellular health, and natural energy production to support overall wellness*
- Brain Health Supplement: Methylcobalamin B12 is essential to help maintain focus and cognitive function, so you can stay alert when it matters most*
- Mood Support Supplement: Supports nervous system function, which helps maintain clarity*
- Non-GMO & Vegan Supplement: EZ Melts makes it easier to take superior quality vitamins—free from artificial flavors, gluten, dairy, soy, and sugar
10. Vitafusion Vitamin B12 Gummies
If you have a sweet tooth, these gummies may be just what you need. Each serving offers 500 mcg of B12 in a great-tasting format.
While it’s a delicious way to get your dose, ensure you don’t overindulge, as these gummies contain added sugars.
Bestseller No. 1
vitafusion Extra Strength Vitamin B12 Gummies, Supports Energy Metabolism and Nervous System Health Support, Gummy Vitamin Supplement for Women and Men, Cherry Flavor, 45 Day Supply, 90 Count
- One 90 count bottle of vitafusion Extra Strength Vitamin B12 Gummy Vitamins, cherry-flavored dietary supplements, enough B12 vitamins for 45 days
- Vitamin B12 supplement gummies support the metabolism of fats and proteins and provide energy support (1), ideal as daily vitamins
- Convenient B12 vitamin gummy supplements are made with natural fruit flavors, have a satisfying chewy texture and are a great alternative to traditional vitamin pills that are hard to swallow
- Adult gummy vitamins made with no high-fructose corn syrup, no artificial sweeteners, no gluten, no dairy and no synthetic FD&C dyes, so you get the health support you need and nothing that you don't
Conclusion
In the quest for the best B12, the options mentioned above represent some of the top-rated products available on Amazon in 2025. When searching for the best B12 supplement for you, consider your specific health needs, dietary preferences, and lifestyle.
With the right approach, adding B12 to your regimen can enhance your overall health and well-being. So why wait? Explore these options and find the best best B12 supplement for your needs today!
Last update on 2026-04-13 / Affiliate links / Images from Amazon Product Advertising API | hishecozy.com is a participant in the Amazon Associate program and will earn from qualifying purchases.
