Finding the best antifungal cream for dogs is essential for keeping our furry friends healthy and comfortable. Fungal infections in dogs can cause itching, redness, and discomfort, making it essential for pet owners to have effective treatment options on hand. In 2025, several antifungal creams available on Amazon stand out for their efficacy, ease of use, and favorable customer reviews.
In this article, we will explore the top 10 antifungal creams for dogs available on Amazon, providing in-depth reviews and insights to help you make the best choice.
Comprehensive Buying Guide for Antifungal Cream for Dogs
Before diving into the products, it’s essential to understand what to look for when buying antifungal cream for your dog.
Understand the Type of Fungus
Different antifungal creams target specific types of fungi. Your veterinarian can help you identify the type affecting your dog. Common fungal infections include yeasts (like Malassezia), ringworm, and dermatitis.
Active Ingredients
Look for products containing effective antifungal agents such as:
- Clotrimazole: Effective against yeast and other fungi.
- Miconazole: A topical antifungal that works on a range of fungal infections.
- Ketoconazole: Another powerful antifungal that treats more severe infections.
Safety and Ingredients
Check for:
- Natural Ingredients: These tend to be gentler on the skin.
- Hypoallergenic Formulations: Helpful for dogs with sensitive skin.
Application Method
The cream should be easy to apply. Products available in tubes or jars often have better control for application.
Vet Recommendations
Always consult your vet before starting any new treatment. A vet’s approval can guide you towards the most appropriate product.
Top 10 Antifungal Creams for Dogs
1. Vet’s Best Antifungal Cream
Vet’s Best Antifungal Cream is a versatile treatment that combines natural ingredients with antifungal agents.
- Ingredients: It contains clotrimazole, aloe, and other soothing botanicals.
- Effectiveness: This cream effectively targets yeast infections and promotes healing.
Overall, this is a favorite among pet owners seeking a natural antifungal treatment without harsh additives.
- Effective Athlete’s Foot, Jock Itch, Ringworm Cream: Our antifungal balm is a clinically proven fungal infection and jock itch treatment. Rid yourself of uncomfortable fungal conditions and feel free and confident in soft, smooth, healthy skin. Physician formulated, with 18 plants, it's a safe and effective alternative to prescription creams, especially those containing steroids
- Itchy, Burning, Cracked, Scaly Skin Relief: Complete relief from itchy, patchy, dry, rashy skin, this antifungal topical is formulated with powerful plant ingredients in clinically researched amounts for fast results you can see and feel. This safe and effective tinea versicolor treatment does not contain skin irritants or harmful ingredients, like parabens, alcohol, or artificial fragrance.
- Zinc Undecylenate And Extra Strength Tea Tree Oil: Our product is formulated with powerful zinc undecylenate which works to treat fungal conditions, plus a high dose of tea tree oil to quickly soothe itching. See results in just days!
- Triple-Action for Truly Healthy Skin: Antifungal, hydrating and protective. The strongest defense against fungal infections is healthy skin, so we formulate our triple-action balm to eliminate fungus while deeply hydrating dry, cracked skin, and protecting your skin's barrier from future infection
- Physician Formulated for Results: Specially formulated by our medically trained physician who has specialized, cutting-edge knowledge of plant based science. Our formula uses only clinically proven dosages for each extensively researched ingredient to ensure efficacy and safety
2. Pet MD Antifungal & Antibacterial Ointment
Pet MD offers a dual-action ointment that not only treats fungal infections but also combats bacterial issues.
- Ingredients: It contains miconazole, which is potent against a variety of fungi.
- Effectiveness: This cream is well-reviewed for quickly alleviating symptoms associated with skin infections.
This product is perfect for pet owners looking for a multi-functional solution.
- MEDICATED CAT & DOG WIPES: Ketoconazole & Chlorhexidine wipes for cats & dogs treat & eliminate skin infections. Great for a dog yeast infection, Fungus, Bacteria, Mange, Ringworm, Hotspots & Pyoderma.
- PERFECTLY SIZED: These chlorhexidine wipes for dogs and cats are wet, small (2.5”x2.5”) and thin enough to fit every crevice such as paws without discomfort. Perfect for hot spot treatment for dogs paws and bacterial, fungal, and yeast infections.
- SOOTHING WIPES: Effective active ingredients with soothing Aloe and Essential Fatty Acids help soothe infected areas. Great for hot spot treatment, mange treatment, pyoderma, ringworm, bacteria, fungal and yeast infection treatment for dogs & cats.
- SATISFACTION GUARANTEED: We guarantee our Antiseptic, Antifungal, and Antibacterial medicated wipes for dogs and cats will help alleviate your cat or dog's skin infections. If it doesn’t work, send us the remaining pads and we'll make it right!
- MADE IN USA: We produce these medicated wipes in our locally and federally regulated facilities. That is how we can guarantee the best treatment for common skin infections for your dog or cat or any animal.
3. Zymox Enzymatic Cream
Zymox’s cream focuses on treating infections using a unique enzymatic approach.
- Ingredients: This product contains natural enzymes that target a range of fungal infections.
- Effectiveness: Many users report significant improvements within days of application.
This is a great choice for those who prefer enzymatic therapy over chemical solutions.
- Provides gentle, soothing relief from skin irritations like itchy skin, hot spots, dermatitis & more
- Pet ointment with hydrocortisone helps manage skin issues without using harsh chemicals
- No-sting lotion means no pre-cleaning is required, making applications less painful
- Made with gentle ingredients that are safe if licked after application; for dogs & cats of all ages
- Veterinarian strength pet formula is ideal for skin irritations to the face, paws & body folds
4. Vet’s Best Allergy Itch Relief
While primarily designed for itch relief, this cream also works on fungal issues thanks to its antifungal properties.
- Ingredients: It features natural ingredients like tea tree oil and aloe.
- Effectiveness: It’s especially helpful for dogs prone to allergies that lead to skin infections.
This is a solid choice for dogs with various sensitivities.
- SUPPORTS NORMAL HISTAMINE LEVELS: Vet’s Best Seasonal Allergy Soft Chews help support normal histamine levels to ease seasonal discomfort and maintain proper skin moisture, helping your dog stay comfortable and non-itchy throughout allergy season.
- VETERINARIAN FORMULATED: Crafted by veterinarians using natural and premium ingredients like Nettle Leaf, Perilla Seed, and Vitamin E, this formula supports your dog’s immune system and skin health for effective allergy relief.
- TASTY SOFT CHEWS: These soft, moist chews are easy to give directly or mixed with your dog’s meals, making daily allergy relief easy; Delicious flavor ensures your dog looks forward to them, helping maintain consistent support through allergy season.
- PET PARENT APPROVED: Infused with antioxidant-rich ocean kelp, these functional chews support digestive health, immune defense, and nutrient absorption—offering seasonal allergy relief for dogs with sensitivities to environmental irritants.
- QUALITY YOU CAN TRUST: We Carry the National Animal Supplement Council (NASC) Quality Seal, reflecting rigorous testing and high manufacturing standards; You can trust Vet’s Best to provide safe, effective allergy relief for your beloved dog.
5. NaturVet Anti-Fungal Spray
NaturVet offers a convenient spray option, ideal for difficult-to-reach areas.
- Ingredients: The formula includes miconazole and natural oils.
- Effectiveness: This spray is praised for its ease of use and fast results, particularly in hard-to-apply areas.
This option is excellent for pet owners seeking a hassle-free application.
- HELPS SUPPORT HEALTHY SKIN - Formulated with powerful ingredients to help soothe red, scaly, greasy, or smelly skin while adding moisture to support skin health.
- USE WITH SHAMPOO – Works best when used between washes of our Antiseptic & Antifungal Shampoo as a complete routine to help maintain healthy skin and coat.
- VET-RECOMMENDED – This paraben-free, non-irritating cat and dog spray helps alleviate your pet's skin and coat that may be affected by environmental stressors.
- FOR DOGS AND CATS – Intended for topical use only, spray on pets over 12 weeks of age. The pleasant smell and soothing, effective relief of symptoms will make you and your pets happy.
- EFFECTIVE & AFFORDABLE – Our products are created with powerful ingredients at an affordable price. We know dogs and cats are more than just pets because we are pet parents too.
6. EcoSMART Organic Pet Care Spray
For pet owners seeking an eco-friendly option, EcoSMART offers an organic antifungal spray.
- Ingredients: Made with plant-based ingredients, it’s gentle yet effective.
- Effectiveness: Customers report improved conditions for mild to moderate infections.
This is a favored product for eco-conscious consumers.
- The information below is per-pack only
- Repels mosquitoes, ticks, gnats and other flying insects for hours.
- DEET FREE formula.
- 100% organic insecticide.
- Completely safe to use around children and pets.
7. Vet’s Best Ear Cleanser for Dogs
While primarily an ear cleaner, it effectively manages yeast infections in the ear.
- Ingredients: Contains soothing aloe, vitamin C, and other natural components.
- Effectiveness: Highly rated for treating ear infections and keeping ears clean.
A wise choice for dog owners dealing with recurrent ear infections.
- COORDINATED TREATMENT - Vet's Best Dog Ear Relief Wash & Dry Cleaner Kit cleans and soothes raw, itchy, and smelly dog ears, and keeps dog's ears fresh and dry between baths.
- FAST AND EFFECTIVE - Ear Relief Wash provides fast, effective relief from red, raw, greasy, itchy, and irritated ears.
- LASTING RESULTS - Ear Relief Dry helps to extend the time between ear cleanings.
- NATURAL INGREDIENTS - Both formulas contain natural ingredients in gentle and soothing combinations, including chamomile, clove oil, tea tree oil, and aloe vera.
- MADE IN THE USA - Both formulas are alcohol-free and non-stinging.
8. SynergyLabs Veterinary Formula Antiseptic Spray
This antiseptic spray is designed for both antifungal and antibacterial action.
- Ingredients: The formulation includes chlorhexidine and other powerful agents.
- Effectiveness: Effective for both superficial and deep skin infections.
This product is suitable for dogs with more severe infections requiring immediate attention.
- HELPS SUPPORT HEALTHY SKIN - Formulated with powerful ingredients to help soothe red, scaly, greasy, or smelly skin while adding moisture to support skin health.
- USE WITH SHAMPOO – Works best when used between washes of our Antiseptic & Antifungal Shampoo as a complete routine to help maintain healthy skin and coat.
- VET-RECOMMENDED – This paraben-free, non-irritating cat and dog spray helps alleviate your pet's skin and coat that may be affected by environmental stressors.
- FOR DOGS AND CATS – Intended for topical use only, spray on pets over 12 weeks of age. The pleasant smell and soothing, effective relief of symptoms will make you and your pets happy.
- EFFECTIVE & AFFORDABLE – Our products are created with powerful ingredients at an affordable price. We know dogs and cats are more than just pets because we are pet parents too.
9. Bertie’s Best Antifungal Cream
Bertie’s Best is a newer product designed for both fungi and bacteria.
- Ingredients: In addition to miconazole, it has calendula and chamomile for soothing effects.
- Effectiveness: Users have noted expedited healing and comfort.
Perfect for pet owners seeking a gentle yet effective option.
- Effective Athlete’s Foot, Jock Itch, Ringworm Cream: Our antifungal balm is a clinically proven fungal infection and jock itch treatment. Rid yourself of uncomfortable fungal conditions and feel free and confident in soft, smooth, healthy skin. Physician formulated, with 18 plants, it's a safe and effective alternative to prescription creams, especially those containing steroids
- Itchy, Burning, Cracked, Scaly Skin Relief: Complete relief from itchy, patchy, dry, rashy skin, this antifungal topical is formulated with powerful plant ingredients in clinically researched amounts for fast results you can see and feel. This safe and effective tinea versicolor treatment does not contain skin irritants or harmful ingredients, like parabens, alcohol, or artificial fragrance.
- Zinc Undecylenate And Extra Strength Tea Tree Oil: Our product is formulated with powerful zinc undecylenate which works to treat fungal conditions, plus a high dose of tea tree oil to quickly soothe itching. See results in just days!
- Triple-Action for Truly Healthy Skin: Antifungal, hydrating and protective. The strongest defense against fungal infections is healthy skin, so we formulate our triple-action balm to eliminate fungus while deeply hydrating dry, cracked skin, and protecting your skin's barrier from future infection
- Physician Formulated for Results: Specially formulated by our medically trained physician who has specialized, cutting-edge knowledge of plant based science. Our formula uses only clinically proven dosages for each extensively researched ingredient to ensure efficacy and safety
10. Furbaby Antifungal Dog Spray
Furbaby offers a versatile spray focused primarily on managing fungal infections.
- Ingredients: It includes apple cider vinegar and essential oils, making for an all-natural formulation.
- Effectiveness: Users report positive results for mild fungal issues, especially with regular use.
This is ideal for pet owners wanting a natural method to combat fungi.
- HELPS SUPPORT HEALTHY SKIN - Formulated with powerful ingredients to help soothe red, scaly, greasy, or smelly skin while adding moisture to support skin health.
- USE WITH SHAMPOO – Works best when used between washes of our Antiseptic & Antifungal Shampoo as a complete routine to help maintain healthy skin and coat.
- VET-RECOMMENDED – This paraben-free, non-irritating cat and dog spray helps alleviate your pet's skin and coat that may be affected by environmental stressors.
- FOR DOGS AND CATS – Intended for topical use only, spray on pets over 12 weeks of age. The pleasant smell and soothing, effective relief of symptoms will make you and your pets happy.
- EFFECTIVE & AFFORDABLE – Our products are created with powerful ingredients at an affordable price. We know dogs and cats are more than just pets because we are pet parents too.
Conclusion
Finding the best antifungal cream for dogs is vital for maintaining their health and happiness. The above products, ranging from creams to sprays, cater to various fungal issues and skin sensitivities. Always remember to consult your veterinarian for the most suitable antifungal solution tailored to your dog’s specific condition.
In 2025, we hope this comprehensive guide equips pet owners with the knowledge and tools needed to effectively combat fungal infections. When choosing an antifungal, make sure to consider the type of infection, active ingredients, and application methods.
By selecting the right product, you can ensure your canine companion enjoys a healthier, happier life.
Last update on 2025-12-25 / Affiliate links / Images from Amazon Product Advertising API | hishecozy.com is a participant in the Amazon Associate program and will earn from qualifying purchases.
