When it comes to maintaining optimal health, Vitamin B12 stands out as an essential nutrient. Known for its important role in energy production, red blood cell formation, and neurological function, it’s crucial to find a high-quality B12 supplement. If you’re searching for the best B12 supplements on Amazon, you’re in luck! This article dives into the top 10 products available, along with a buying guide to help you make the best choice for your health.
Bestseller No. 1
Nature Made Vitamin B12 1000 mcg, Dietary Supplement for Energy Metabolism Support, 150 Softgels, 150 Day Supply
- Energy metabolism support supplement: contains one 150 count bottle of Nature Made Vitamin B12 1000 mcg Softgels for a 150 day supply(1)
- These Nature Made Vitamin B12 softgels help break down food into energy that your body can use all day long
- B-12 vitamin helps support brain cell function and mood health (2)
- Vitamin B12 is important for proper red blood cell formation and helps reduce fatigue for those low in B12 vitamins
- Adults take one B 12 vitamin softgel daily with water and a meal
Bestseller No. 2
EZ Melts Dissolvable B12 2,500 mcg - Vitamin B12 for Energy & Immune Support - Non-GMO, Vegan & Gluten-Free - Red Cherry - 90 Sublingual Tablets (90 Servings)
- Vitamin B12 Supplement: EZ Melts B12 are dissolvable tablets that deliver 2,500 mcg of vitamin B12 per serving for easy metabolic energy support*
- Energy Support Supplement: Supports healthy energy levels, cellular health, and natural energy production to support overall wellness*
- Brain Health Supplement: Methylcobalamin B12 is essential to help maintain focus and cognitive function, so you can stay alert when it matters most*
- Mood Support Supplement: Supports nervous system function, which helps maintain clarity*
- Non-GMO & Vegan Supplement: EZ Melts makes it easier to take superior quality vitamins—free from artificial flavors, gluten, dairy, soy, and sugar
OFF -$9.50Bestseller No. 3
Nature Made Maximum Strength Vitamin B12 5000 mcg, Dietary Supplement for Energy Metabolism Support, 60 Softgels, 60 Day Supply
- Energy metabolism support supplement(1): contains one 60 count bottle of Nature Made Maximum Strength Vitamin B 12 5000 mcg Softgels for a 60-day supply
- Vitamin B12 supplements help break down food into energy that your body can use all day long
- Nature Made B12 Vitamins 5000 mcg helps support brain cell function and mood health(3)
- Vitamin B12 is important for proper red blood cell formation and helps reduce fatigue for those low in B12 vitamins
- Adults, take one Vitamin B-12 softgel daily with water and a meal
Bestseller No. 4
Nature's Bounty Vitamin B12 1000 mcg Supplements, Supports Energy Metabolism, 200 Ct
- SUPPORTS CELLULAR ENERGY HEALTH (1): Nature's Bounty Vitamin B-12 1000 mcg aids in converting food into cellular energy (1)
- CARDIOVASCULAR SUPPORT (1): Vitamin B-12 supplements contribute to the health of your cardiovascular and circulatory systems (1)
- MAINTAINS HEALTHY NERVES (1): Great for nerve health, B-12 vitamin helps maintain healthy nerve cells (1)
- EASY TO SWALLOW: These Vitamin B-12 tablets are coated so they are easy to swallow, providing convenience in your daily vitamin regimen
- TRUSTED WELLNESS: From trusted wellness experts, these B-12 Vitamins are made with quality ingredients, backed by 50 years of scientific research
Bestseller No. 5
THORNE - Vitamin B12 - as Methylcobalamin - Supports Heart & Nerve Health, Blood Cell Function, Healthy Sleep & Methylation* - Gluten, Dairy & Soy-Free - 60 Servings
- Active B12: Each capsule provides 1 mg vitamin B12 as methylcobalamin, which is more efficiently used by the body compared to other forms of vitamin B12, like cyanocobalamin
- Heart & Brain Health: Supports a normal level of homocysteine in the body to benefit healthy cardiac function, blood cell formation, and optimal nerve function*
- Sleep Support: Helps maintain normal circadian rhythms to support restful sleep and supports healthy methylation processes in the body*
- Third-Party Certified: This product has been third-party tested and certified to verify what's in the package matches what's on the label and to confirm it contains no unsafe levels of contaminants
- Trusted: Thorne is chosen by champions and trusted by 100+ professional sports teams, a proud partner of U.S. National Teams, and the #1 recommended clinical brand by health-care practitioners (2023 Health-Care Practitioner Seller Survey)
Bestseller No. 6
Nature’s Bounty Vitamin B12 5000 mcg Sublingual Liquid, Cardiovascular Health & Cellular Energy Support, 2 Fl Oz (1 Count)
- CELLULAR ENERGY SUPPORT (1) Nature’s Bounty Vitamin B-12 Sublingual Liquid plays an important role in energy metabolism (1); it helps the body convert food into cellular energy your body needs (1)
- SUPPORTS HEART HEALTH (1) Nature’s Bounty Vitamin B-12 is commonly used to support the health of the cardiovascular and circulatory systems (1); Vitamin B-12 is also an important vitamin for maintaining healthy nerve cells (1)
- EASY-TO-TAKE LIQUID Nature’s Bounty Vitamin B-12 Sublingual Liquid makes it easy to get your daily dose of this essential nutrient; Simply place 1 mL daily under the tongue and hold there for 30 seconds before swallowing; You’ll love the delicious, natural berry flavor
- QUALITY IS OUR PRIORITY Nature’s Bounty is committed to the safety of all of our supplements; Our Vitamin B-12 liquid is gluten free; sugar free; contains no artificial colors or flavors; and is suitable for vegetarians
- FROM THE TRUSTED WELLNESS EXPERTS Nature’s Bounty Vitamin B-12 Sublingual Liquid is a product of nearly 50 years of dedication to quality; consistency and scientific research to make vitamins and nutritional supplements of unrivaled excellence
Bestseller No. 7
Doctor's Best Fully Active B12 1500 mcg, Non-GMO, Vegan, Gluten Free, Supports Healthy Memory, Mood and Circulation, 60 Count
- FULLY ACTIVE B-12 - vitamin B12 methylcobalamin is the most active form of B-12 that supports energy production. Supports memory essential for brain health and function, energy metabolism and the production of red blood cells.*
- FEEL MORE ENERGIZED - Vitamin B12 plays an important role in the body's energy production and protection of the nervous system, and taking a daily supplement can help maintain adequate levels in the body.*
- MEMORY AND FOCUS - Vitamin B12 plays an important role in helping your nervous system function. Studies have shown it improves memory and focus, as well as your ability to learn.*
- SUPPORTS ENERGY, BRAIN FUNCTION & RED BLOOD CELLS - an effective 1500 mcg dose is ideal for supporting energy levels and metabolism, the central nervous system, mood & red blood cell production.*
- BETTER ABSORPTION - methylcobalamin is considered the active form of vitamin B12, meaning it can be directly used by the body without needing further conversion, making it the most readily absorbed and utilized form of B12.*
Bestseller No. 8
Pure Encapsulations B12 Folate - Energy Supplement to Support Nerves, Energy Metabolism & Cognitive Support* - with Vitamin B Folate as Metafolin - 60 Capsules
- Premium Folate Supplement: Vitamin B12 and folate help convert carbohydrates into energy and break down proteins in the body; provides metabolism support*
- Nervous System Support: Vitamin B12 (methylcobalamin) and folate (L-5-MTHF) support the nervous system, and function as hair, skin, and liver aids.*
- Cognitive Support: Folate is essential for fetal neural development; B12 is an important nutrient for memory and cognitive support*
- Supports Gut Health: Support G.I. tract thanks to the active form of the B12 vitamin, methylcobalamin; also a liver support supplement*
- Pure Difference: What we leave out matters, too; Pure Encapsulations products are free from common allergens, artificial or unnecessary ingredients, and GMOs
Bestseller No. 9
Jarrow Formulas Methyl Vitamin B12 5000 mcg - 60 Chewable Tablets, Naturally Fruit Flavored- Bioactive B12 Vitamin - Supports Cellular Energy Production, Brain Health & Metabolism - 60 Servings
- Cellular Energy Production and Brain Health support supplement: Contains one 60 count bottle of Jarrow Formulas Maximum Strength Methyl B-12 5000 mcg Chewable Tablets for a 60-day supply.
- Each cherry-flavored chewable tablet provides a high amount of Methyl B-12 for benefits such as helping to support cellular energy production, maintaining brain health, and sleep.
- Methyl B-12 is better absorbed and retained by the body than cyanocobalamin, providing nutritional support for people with Vitamin B12 deficiency, vegetarians, vegans, and people over 50.
- Suggested Use: Adults, take one chewable tablet once a day or as directed by your qualified healthcare professional.
- These statements have not been evaluated by the Food and Drug Administration; this product is not intended to diagnose, treat, cure, or prevent any disease.
OFF -$2.28Bestseller No. 10
Nature Made Vitamin B12 1000 mcg, Easy to Take Vitamin B12 Sublingual Tablets for Energy Metabolism Support, 150 Sugar Free Fast Dissolve Tablets, 150 Day Supply
- Energy metabolism support supplement(1): contains one 150 count bottle of Nature Made Sublingual B12 1000 mcg Fast Dissolve Tablets for a 150-day supply
- Nature Made B12 1000mcg tablets help break down food into energy that your body can use all day long
- B-12 vitamin helps support brain cell function and mood health(2)
- Vitamin B12 supplements provide B12, which is important for proper red blood cell formation and helps reduce fatigue for those low in B12 vitamins
- Easy to take with a great tasting flavor; simply dissolve one B12 1000 mcg sublingual tablet under tongue before swallowing. Adults take one Vitamin B12 tablet daily with a meal
Buying Guide: How to Choose the Best B12 Supplement
Selecting the best B12 supplement can be overwhelming given the vast options available. Here’s a brief guide to help you make an informed decision:
1. Forms of B12
- Methylcobalamin: This is the most bioactive form and often recommended for its superior absorption and efficacy.
- Cyanocobalamin: While this synthetic form is stable and widely used, it must be converted into an active form by your body.
- Other Forms: B12 is also available as adenosylcobalamin and hydroxocobalamin, which are beneficial in various contexts.
2. Dosage
- Typical dosages range from 500 mcg to 5000 mcg. Your needs may vary based on dietary restrictions, lifestyle, and health conditions.
3. Additional Ingredients
- Some supplements come with added nutrients like folic acid, Vitamin D, or herbal extracts, which can amplify the health benefits.
4. Delivery Method
- B12 supplements come in various forms, including tablets, sublingual lozenges, sprays, and gummies. Choose one that fits your preference.
5. Quality and Brand Reputation
- Look for products that are third-party tested for quality and free from harmful additives.
6. Vegetarian or Vegan Options
- If you’re following a plant-based diet, make sure to choose B12 sourced from non-animal origins.
With these points in mind, let’s delve into the best B12 supplements available on Amazon in 2025.
Top 10 B12 Supplements on Amazon
1. Nature Made Vitamin B12 1000 mcg
Nature Made offers a reputable B12 supplement that is free from gluten and artificial colors. Each tablet provides 1000 mcg of cyanocobalamin, making it suitable for most adults.
This product is known for its high absorption rate, but it may require a doctor’s approval for those with certain medical conditions.
Bestseller No. 1
Nature Made Vitamin B12 1000 mcg, Dietary Supplement for Energy Metabolism Support, 150 Softgels, 150 Day Supply
- Energy metabolism support supplement: contains one 150 count bottle of Nature Made Vitamin B12 1000 mcg Softgels for a 150 day supply(1)
- These Nature Made Vitamin B12 softgels help break down food into energy that your body can use all day long
- B-12 vitamin helps support brain cell function and mood health (2)
- Vitamin B12 is important for proper red blood cell formation and helps reduce fatigue for those low in B12 vitamins
- Adults take one B 12 vitamin softgel daily with water and a meal
2. Garden of Life mykind Organic B12 Spray
Formulated in a convenient spray form, this organic B12 supplement uses methylcobalamin for better absorption and is free from artificial additives.
It’s also certified USDA organic, making it a great choice for health-conscious consumers. The spray is easy to use and has a pleasant taste, though the size may be less familiar for some.
OFF -$6.46Bestseller No. 1
Garden of Life Organics B12 Vitamin - Whole Food B-12 for Metabolism and Energy, Raspberry, 2oz Liquid
- ENERGY SUPPLEMENT: One spray daily delivers 500 Microgram (8333percentage DV) vegan vitamin B12 as methyl cobalamin to support energy, metabolism, and heart health*
- VITAMIN B12: Essential to protect the body against anemia and support a healthy central nervous system, B12 vitamin helps maintain healthy nerve cells and red blood cells and is also needed to make DNA, the genetic material in all cells*
- CONCENTRATION SUPPLEMENT: This whole food B12 concentration spray are made from real, nutritious foods
- LIQUID VITAMIN: Our organic liquid vitamin B12 comes in delicious, mouth watering raspberry spray
- ORGANIC VITAMIN: Our real food B12 vitamin is Certified USDA Organic, Non GMO Verified, Vegan, Gluten Free Certified, and Kosher Made
3. Solgar Vitamin B12 1000 mcg Nuggets
Solgar’s B12 nuggets utilize methylcobalamin to support energy production and overall well-being. The nuggets dissolve quickly under the tongue, contributing to rapid absorption.
This brand is well-regarded for its commitment to quality, although its larger nugget size might be a minor inconvenience for some.
Bestseller No. 1
Solgar Vitamin B12 1000 mcg, 250 Nuggets - Supports Production of Energy, Red Blood Cells - Healthy Nervous System - Promotes Cardiovascular Health - Vitamin B - Non-GMO, Gluten Free - 250 Servings
- Energy Support; Vitamin B12 is part of a group of essential nutrients known as the B Complex; It supports energy metabolism and promotes a healthy nervous system
- Supports Heart Health; B12 supports heart health by promoting healthy levels of homocysteine already within a normal range; It also assists in the regeneration of red blood cells, which help to deliver oxygen throughout the body
- Convenient Dosage; Solgar Sublingual 1000 mcg Vitamin B12 nuggets melt under the tongue for fast, easy absorption
- Non-GMO, Kosher & Gluten Free; Solgar Vitamin B12 nuggets are suitable for vegans; Free of: gluten, wheat, dairy, soy, yeast, sugar, sodium, artificial flavor and color
- The Gold Standard: For over 70 years, Solgar has been committed to quality, health, and well-being. Our mission is to create the finest nutritional supplements in small batches, through tireless research, using only the finest raw materials
4. NOW Foods B-12 5000 mcg
For those needing higher doses, NOW Foods B-12 provides each serving with an impressive 5000 mcg of methylcobalamin.
This option is especially suitable for individuals who may be deficient due to lifestyle or dietary habits. However, those new to B12 may want to start with a lower dosage.
Bestseller No. 1
NOW Foods Supplements, Methyl B-12 (Methylcobalamin) 5,000 mcg, Nervous System Health*, 120 Lozenges
- ESSENTIAL FOR ENERGY PRODUCTION*: Vitamin B-12 is necessary for the production of energy from fats and proteins and is well known for its critical role in DNA synthesis, as well as in homocysteine metabolism*
- METHYLCOBALAMIN PLUS FOLIC ACID: Methyl B-12 is vegetarian/vegan (non-animal derived)
- CERTIFICATIONS/CLASSIFICATIONS: Kosher, Soy Free, Vegan
- GMP Quality Assured: A-rated, third-party certification means that every aspect of the NOW manufacturing process has been examined. Our in-house laboratories are ISO/IEC accredited for laboratory testing including for stability, potency and product formulation.
- Packaged in the USA by a family owned and operated company since 1968
5. Jarrow Formulas Methyl B-12 1000 mcg
Jarrow’s formulation features high-potency methylcobalamin designed for fast sublingual absorption. This product is ideal for vegans and vegetarians and is free from common allergens.
The taste is more pleasant compared to traditional B12 tablets but may be more suited for individuals familiar with sublingual supplements.
Bestseller No. 1
Jarrow Formulas Methyl Vitamin B-12 1000 mcg, 100 Chewable Tablets, Lemon Flavored- Bioactive B12 Vitamin - Supports Cellular Energy Production, Brain Health & Metabolism - 100 Servings
- Cellular Energy Production and Brain Health support supplement: Contains one 100 count bottle of Jarrow Formulas Extra Strength Methyl B-12 1000mcg Chewable Tablets for a 100-day supply.
- Easy-to-take, lemon-flavored chewable tablets to help maintain brain health, and support sleep.
- Dietary supplement with Methyl B-12, the active form of Vitamin B12, which is delivered more effectively to support your bodys natural cellular energy production.
- Suggested Use: Adults, dissolve in the mouth or chew one tablet per day or as directed by your qualified healthcare professional.
- These statements have not been evaluated by the Food and Drug Administration; this product is not intended to diagnose, treat, cure, or prevent any disease.
6. MaryRuth Organics Liquid B12
Liquid B12 is a great alternative for those who have difficulty swallowing pills. This vegan-friendly option is made with methylcobalamin and is sweetened using organic cane sugar.
While the taste is quite good, dosing may require more care compared to traditional capsules.
Bestseller No. 1
MaryRuth Organics Vitamin B12 Liquid Spray | Vegan, Non-GMO, Gluten-Free | USDA Organic Supplement | Energy & Nervous System Support | B12 Vitamins for Women & Men | 1,500 mcg | 1 Fl Oz
- Boost Energy and Brain Health with B12 Vitamins: Our USDA Organic Vegan B12 Spray maintains normal energy levels and supports brain health! Ideal for those with an MTHFR gene variant; enjoy the benefits of vitamin B12 without compromising your diet—an effortless way to incorporate a b12 supplement into your wellness routine with a delicious berry flavor, supporting your brain, nervous system, and red blood cells!
- Travel-friendly :Perfect for busy travelers; ensure you never miss a b12 vitamin intake again with our compact spray that fits effortlessly into any handbag or backpack, providing a quick and convenient boost to your energy levels and mood, anytime, anywhere.
- Vegan : Integrate into your vegan lifestyle effortlessly; our vegan B12 formula supports cognitive function, and provides energy to those who are deffiicent. B12 also aids the body in DNA synthesis and red cell production. If you have an MTHFR gene variant, like MaryRuth herself, this might be the best type of B12 for you!
- Enhanced Absorption: Our natural berry flavored B12 Spray is made with methylcobalamin, which has superior bioavailability to cyanocobalamin! B12 also aids the body in DNA synthesis and red blood cell production.
- For Most Lifestyles: MaryRuth's Methyl B-12 vitamin Spray is USDA Organic, Vegan, Non-GMO, Dairy Free, Nut Free, Gluten Free, Soy Free, Sugar Free, Made in a GMP Facility. Clean Label Project Certified. B Corp Certified.
7. Clinical Effects B12
Clinical Effects offers a potent vegan B12 supplement with 3000 mcg of methylcobalamin per serving.
The product comes in a spray form, making it convenient and easy to use. However, some users may find the flavor to be on the artificial side.
Bestseller No. 1
BioActive Vitamin B Complex - Blood Stream Ready, Methylated B Complex - Featuring Methylfolate, 3 BioActive Forms of B12, BenfoPure® B1 & Pantesin® B5 - 12 B Vitamins in Clinical Doses - 60 Servings
- ACTIVE & METHYLATED FORMS FOR MAX ABSORPTION: Each B vitamin is delivered in its bloodstream-ready, active or methylated form—no extra processing required. This means faster, more effective results for energy, metabolism, and overall vitality.*
- FULL-SPECTRUM, BIOACTIVE FORMS OF B12 COMPLEX: Features Methyl B12, Adenosyl B12, and Hydroxo B12 to ensure both immediate and long-lasting B12 availability, optimizing cellular energy production and detox support.*
- L-METHYLFOLATE (5-MTHF) FOR SUPERIOR FOLATE SUPPORT: Utilizes the most bioactive form of B9 to enhance cognitive function, support healthy mood, and maintain proper homocysteine levels, especially vital for those with methylation difficulties.*
- PREMIUM BenfoPure® B1 & Pantesin® B5 FOR BETTER PERFORMANCE: BenfoPure® Benfotiamine (B1) and Pantesin® Pantethine (B5) deliver up to 500% more effectiveness than standard forms, fueling heart health, nerve function, and efficient metabolism.*
- Supports Total Body Health: Experience comprehensive whole-body wellness—from boosting energy, cognitive function, and mood balance to supporting heart health, healthy stress response, optimal metabolism, and radiant hair, skin, and nails—all through the superior absorption of fully active, methylated B vitamins.*
8. Nutricost Vitamin B12 5000 mcg
Nutricost provides a high-dose B12 supplement in an easy-to-swallow capsule form, making it preferable for those who dislike sprays or lozenges.
This product is gluten-free and non-GMO, although potential buyers should note that it contains gelatin.
Bestseller No. 1
Nutricost Vitamin B12 (Methylcobalamin) 5000mcg, 240 Capsules - Vegetarian Caps, Non-GMO, Gluten Free B12 Supplement
- 5000mcg (5mg) of Vitamin B12 Per Serving
- 240 Servings Per Bottle, 1 Capsule is 1 Serving
- Vegetarian, Non-GMO & Gluten Free
- Each Batch is Tested by Independent, ISO-Accredited Laboratories
- Made in an NSF Certified, GMP Compliant, FDA Registered Facility.
9. EZ Melts B12 1000 mcg
EZ Melts delivers a unique twist with its melt-in-your-mouth technology, making it easy to absorb while enjoying delicious flavors.
It’s suitable for both vegetarians and vegans, though the price point might be higher compared to traditional pills.
Bestseller No. 1
EZ Melts Dissolvable B12 2,500 mcg - Vitamin B12 for Energy & Immune Support - Non-GMO, Vegan & Gluten-Free - Red Cherry - 90 Sublingual Tablets (90 Servings)
- Vitamin B12 Supplement: EZ Melts B12 are dissolvable tablets that deliver 2,500 mcg of vitamin B12 per serving for easy metabolic energy support*
- Energy Support Supplement: Supports healthy energy levels, cellular health, and natural energy production to support overall wellness*
- Brain Health Supplement: Methylcobalamin B12 is essential to help maintain focus and cognitive function, so you can stay alert when it matters most*
- Mood Support Supplement: Supports nervous system function, which helps maintain clarity*
- Non-GMO & Vegan Supplement: EZ Melts makes it easier to take superior quality vitamins—free from artificial flavors, gluten, dairy, soy, and sugar
10. Vitafusion Vitamin B12 Gummies
If you have a sweet tooth, these gummies may be just what you need. Each serving offers 500 mcg of B12 in a great-tasting format.
While it’s a delicious way to get your dose, ensure you don’t overindulge, as these gummies contain added sugars.
OFF -$0.81Bestseller No. 1
vitafusion Extra Strength Vitamin B12 Gummies, Supports Energy Metabolism and Nervous System Health Support, Gummy Vitamin Supplement for Women and Men, Cherry Flavor, 45 Day Supply, 90 Count
- One 90 count bottle of vitafusion Extra Strength Vitamin B12 Gummy Vitamins, cherry-flavored dietary supplements, enough B12 vitamins for 45 days
- Vitamin B12 supplement gummies support the metabolism of fats and proteins and provide energy support (1), ideal as daily vitamins
- Convenient B12 vitamin gummy supplements are made with natural fruit flavors, have a satisfying chewy texture and are a great alternative to traditional vitamin pills that are hard to swallow
- Adult gummy vitamins made with no high-fructose corn syrup, no artificial sweeteners, no gluten, no dairy and no synthetic FD&C dyes, so you get the health support you need and nothing that you don't
Conclusion
In the quest for the best B12, the options mentioned above represent some of the top-rated products available on Amazon in 2025. When searching for the best B12 supplement for you, consider your specific health needs, dietary preferences, and lifestyle.
With the right approach, adding B12 to your regimen can enhance your overall health and well-being. So why wait? Explore these options and find the best best B12 supplement for your needs today!
Last update on 2025-12-26 / Affiliate links / Images from Amazon Product Advertising API | hishecozy.com is a participant in the Amazon Associate program and will earn from qualifying purchases.
