Methylene blue supplements are gaining prominence in the wellness and supplement community due to their potential benefits for cognitive function, energy enhancement, and mitochondrial health. If you’re on the prowl for the best methylene blue supplement on Amazon, you’re in the right place. In this article, we’ll explore the top 10 products available on Amazon in 2025, providing in-depth reviews so you can make an informed decision.
- đźš« WARNING đźš« Do NOT take if on SSRIs. Do NOT take if pregnant or nursing. Not for children. May interact with a large number of medications - consult a doctor if on any medications before taking. Interacts with common allergy medications such as Benadryl. Methylene Blue is a powerful compound, do your research before consuming. Search online for possible adverse reactions (a list is available on our website). Taking in the evening could impact sleep.
- âś” Trusted Made in America Brand. Family Owned Small Business. Focused on Cellular Health and Wellness
- âś” Made with Vitamin C Ester for Enhanced Absorption and bioavailibiliy. Vitamin C helps Methylene Blue form LeucoMethylene Blue, a colorless form that may mitigate blue urine or blue staining.
- âś” Combined with Organic Cacao Powder which has coco flavonoids.
- âś” 60 Capsules - Vegetarian Capsules - 60 day supply - Capsule form rather than liquid form (No staining, absorbed in gut better)
- Methylene Blue Drops
- METHYLENE BLUE SUPPLEMENT - Each capsule delivers 10mg of 99% pure blue methylene pharmaceutical grade. Crafted for individuals seeking a clean, lab-verified source of support.*
- CELLULAR & MITOCHONDRIAL FUNCTION SUPPORT - Formulated to assist in maintaining healthy mitochondrial efficiency and daily cellular activity. Key for natural energy balance and cognitive clarity.*
- THIRD-PARTY TESTED - Purity You Can Trust. Every batch of our methylene blue pills are independently tested for purity, identity, and consistency. Ensuring pharmaceutical grade quality from start to finish.*
- CLEAN INGREDIENTS - Formaldehyde Free Formula, Just the essentials. delivered in a vegetable capsule for simple, everyday use.*
- USA MADE - Manufactured in a GMP-certified U.S. facility in Utah with full traceability and strict oversight. Designed for precision and purity.*
- Premium Pharmaceutical Grade - Made with USP grade methylene blue at a 3% concentration to deliver reliable quality for those focused on brain and cellular health.
- Cognitive Function Support - Formulated to help enhance focus, memory, and mental performance, making it a useful nootropic for everyday clarity.
- Promotes Cellular Energy - Supports healthy mitochondrial activity, encouraging better oxygen utilization and natural energy production at the cellular level.
- Clean and Pure Formula - Completely free from formaldehyde, alcohol, and unnecessary additives, offering a safe choice for daily wellness routines.
- Easy to Use Large Bottle - Packaged in a generous 4.06 fl oz (120 mL) glass bottle with dropper for precise dosing, convenient use, and an extended supply.
- 2% ULTRA CONCENTRATION: Less Drops to be Effective and double the amount of anyone else.
- 1% Methylene Blue trihydrate, demineralized water. Pharma grade ingredients: Demineralized water (EP, USP), Methylene blue (USP). Third-Party Tested.
- 1 vertical drop contains 0.5 mg of Methylene Blue.
- Directions: Mix 1 ml (20 drops) of the solution with 200 ml of water, or use according to your established research protocols.
- Our premium dark amber glass bottle with glass dropper/pipette protects methylene blue from sunlight and oxidation, ensuring long-lasting purity and maximum effectiveness. Securely packed in a durable, heavy-duty cardboard tube – perfect for travel and on-the-go protection.
- Third-Party Tested for Heavy Metal Contamination and microbiology. Upon request, a heavy metal analysis and microbiology analysis will be provided. Our product meets and exceeds USP requirements. Third-Party (USP) United States Pharmacopeia verified methylene blue incl. certificate.
Navigating the myriad of options can be overwhelming, but with the right guidance, you can definitely find the best methylene blue supplement that fits your needs. Here are our top picks:
1. Pure Encapsulations Methylene Blue 99% Powder
Pure Encapsulations is a well-respected brand known for its high-quality dietary supplements. Their Methylene Blue 99% Powder is no exception.
Features:
- Form: Powder
- Purity: 99%
- Non-GMO: This product is free from genetically modified organisms.
- Directions: Mix with water or juice.
Review:
Pure Encapsulations has perfected the art of purity. Their methylene blue powder offers a convenient method to add this supplement to your regimen. It is free from allergens and is highly bioavailable, ensuring better absorption.
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2. Methylene Blue by Blue Sky
Blue Sky’s Methylene Blue is a liquid formulation that focuses on quality and efficacy.
Features:
- Form: Liquid
- Concentration: High concentration for immediate effects.
- Vegan: Suitable for vegan lifestyles.
Review:
This liquid formulation is perfect for those who struggle with powders. The concentration is aligned with clinical practices, providing a quick and efficient way to supplement.
- Enhances Well-being - Our exclusive formulation of methylene blue is made to bolster the mitochondria's energy-generating processes, enhancing cerebral blood flow and oxygenation.
- Supports Antioxidant Activity - Our top-quality methylene blue is rich in antioxidants, essential for minimizing oxidative stress by neutralizing free radicals.
- Boosts Energy and Metabolism - By encouraging autophagy, methylene blue aids in sustaining cellular vitality and preventing the build-up of detrimental substances.
- Superior Quality and Safety Measures - Packaged in glass bottles to ensure ease of use and maintain efficacy, our USP-grade methylene blue for human consumption is subject to strict quality control checks for unmatched purity and safety.
- Love It or Return It - Committed to the excellence of our product, we offer returns. Consult your healthcare practitioner prior to use. Not for pregnant or nursing women.
3. BulkSupplements Methylene Blue Powder
BulkSupplements is known for its focus on transparency and quality. Their Methylene Blue Powder is another solid choice.
Features:
- Form: Powder
- Laboratory Tested: Verified for purity.
- No Fillers or Additives: Pure Methylene Blue.
Review:
This product is ideal for those looking for value without compromising quality. The powdered form lets you adjust your dosage easily.
- Boost Memory & Cognitive Function: USP-grade methylene blue supports mitochondrial energy production, enhances blood flow and oxygen delivery to the brain, and may help improve memory, focus, and mental clarity for peak daily performance
- Powerful Antioxidant Protection: Pharmaceutical-grade methylene blue acts as a potent antioxidant, neutralizing harmful free radicals, reducing oxidative stress, and supporting cellular health for overall vitality and longevity
- USP Pharmaceutical Grade: 99.8% Ultra-Pure – Our methylene blue powder meets USP/NF standards, each 25g bottle, and every batch of our methylene blue powder undergoes rigorous third-party testing to ensure high purity, no formaldehyde contamination
- Easy to Prepare & Use: Pre-diluted solution guide: Mix 1g methylene blue powder + 100ml water = 1% methylene blue solution (1 scoop = 1g). Water-soluble for fast, consistent results
- Professional-Grade Quality: Our methylene blue powderhas strong dyeing power, may temporarily turn urine/tongue blue-green, but it is harmless, so wear gloves during preparation to avoid skin/clothing stains
4. Klean Athlete Methylene Blue
Designed for athletes, Klean Athlete has made a name for itself with clean and effective supplements.
Features:
- Form: Capsules
- Focus on Performance: Enhanced energy and mitochondrial support.
Review:
Klean Athlete’s capsules offer a pre-measured dose of methylene blue, making it easy to incorporate into your routine. Their commitment to clean ingredients speaks volumes to their brand integrity.
- 1% USP Grade Methylene Blue Solution: Highly purified formula standardized at 10 mg/mL (0.5 mg/drop) for consistent quality. Prepared in a cGMP certified facility with strict manufacturing standards.
- Made in the USA with Human Safety in Mind: Formulated and bottled in the United States. Designed for quality and compliance. User-friendly, helping support mental clarity, cellular energy, and healthy aging.
- Lab-Tested for Purity & Safety:Third-party tested for heavy metals (As, Cd, Cu, Hg, Pb, Se, Sn, Zn). Free from formaldehyde, preservatives, or unnecessary additives.
- Suggested Use: Begin with 10 drops (5mg) in water twice daily. If well tolerated, gradually increase: Week 2 – 20 drops twice daily; Week 3 – 30 drops twice daily. Each drop contains ~0.5mg (10mg/mL). Common upper reference: 1–2 mg/kg/day in divided servings.
- Trusted Quality in Amber Glass Dropper Bottle: Dark amber glass helps preserve formula strength, while the precision dropper makes dosing simple and mess-free. Popular among researchers and wellness users alike for supporting brain clarity, cellular energy, and healthy aging from within.
5. Herb Performance Methylene Blue Capsules
Herb Performance focuses on holistic health and performance-related supplements.
Features:
- Form: Capsules
- Holistic Focus: Aimed at enhancing cognitive and physical performance.
Review:
These capsules are designed for users looking to boost both cognitive and physical performance. The encapsulated form is convenient and makes it easy to adhere to a daily regimen.
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6. Elysium Methylene Blue
Elysium’s Methylene Blue supplement is formulated for biohackers and those invested in longevity.
Features:
- Form: Powder
- Focus on Longevity: Claims to support cellular health.
Review:
With an eye on longevity and performance, Elysium’s product targets both the brain and overall cellular health.
- 2% ULTRA CONCENTRATION: Less Drops to be Effective and double the amount of anyone else.
7. Doctor’s Best Methylene Blue
Doctor’s Best is a brand trusted by healthcare professionals for its clinically backed formulations.
Features:
- Form: Capsules
- Health-Focused: Promotes brain health and energy levels.
Review:
Packed in a capsule, Doctor’s Best makes it easy to incorporate methylene blue into a diet. Their research-backed approach provides assurance regarding the efficacy of their products.
- PHARMACEUTICAL-GRADE PURITY – Each serving delivers 10 mg of 1% USP methylene blue, third-party tested to ensure consistency and quality.
- FOCUS & MENTAL CLARITY SUPPORT – Formulated to help maintain healthy concentration and clear thinking as part of your daily wellness routine.
- CLEAN, DOCTOR-FORMULATED – Crafted with purified water and no formaldehyde, GMOs, gluten, alcohol, or artificial additives.
- PRECISE GLASS DROPPER – Calibrated to a 20-drop (1 mL) serving; take sublingually or mix into water or juice for easy, accurate dosing.
- MADE IN USA, GMP-CERTIFIED – Produced in a GMP-certified facility by Dr. Robaina, leveraging over 30 years of natural wellness expertise.
8. Nutrastar Methylene Blue
Nutrastar focuses on natural ingredients and methods.
Features:
- Form: Powder
- Natural Ingredients: No artificial additives.
Review:
Combining natural ingredients offers users a complementary approach to methylene blue supplementation. The powder allows for versatility in consumption, whether mixed in drinks or taken plain.
- 2% ULTRA CONCENTRATION: Less Drops to be Effective and double the amount of anyone else.
9. Amazing Formulas Methylene Blue
Amazing Formulas is known for making quality supplements affordable.
Features:
- Form: Capsules
- Budget-Friendly: A great option without breaking the bank.
Review:
Amazing Formulas presents a solid option for those on a budget looking for the benefits of methylene blue. The capsules are easy to swallow and come with clear dosage instructions.
- Premium Quality & Purity: Our Methylene Blue Drops are manufactured in the USA with the highest standards. Blue Methylene supplement is USP Grade lab-tested for purity and potency to ensure a consistent and reliable product.
- Lab Tested: Carefully crafted in state-of-the-art facilities, each batch of methylene blue for humans undergoes rigorous third-party testing to meet quality benchmarks you can trust.
- USA-Made Excellence: Proudly made in the USA, our Methylene Blue is produced following strict GMP (Good Manufacturing Practices) for exceptional quality assurance.
- Pure & Potent Formula: Designed with precision, this product offers an uncompromised formulation with high-grade ingredients for optimal results in every drop.
- Trustworthy Manufacturing Process: We prioritize safety and quality, adhering to stringent testing and production protocols to deliver a product you can rely on confidently. Azul De Metileno
10. Natural Stacks Methylene Blue
Natural Stacks emphasizes open-source ingredients and research-backed formulations.
Features:
- Form: Capsules
- Focus on Transparency: Clear ingredient disclosures.
Review:
Natural Stacks’ commitment to transparency makes it stand out. Their methylene blue capsules focus on enhancing brain health while maintaining a high standard of ingredient quality.
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Buying Guide for Methylene Blue Supplements
Methylene blue supplements can be a valuable addition to your wellness routine, but selecting the right one is crucial. Here are some factors to consider:
1. Formulation Type
- Powder vs. Capsules: Powders allow for versatility in dosing, while capsules are convenient for on-the-go users.
2. Purity and Quality
- Look for products with high purity levels, typically around 99%. Third-party testing is a good indicator of reliability.
3. Brand Reputation
- Choose brands with positive reviews and robust customer service records. Research their sourcing and manufacturing practices.
4. Intended Use
- Determine if you’re looking for cognitive enhancement, energy boosting, or overall cellular health, and select accordingly.
5. Cost-Effectiveness
- Consider not just the price but the value offered in terms of quality and dosage per serving.
6. Allergens and Additives
- Check the ingredient list for allergens or unwanted additives like artificial colors, flavors, or binders.
7. Reviews and Testimonials
- User experiences can offer valuable insights into the effectiveness of a supplement.
By considering these factors, you can make an informed decision and find the best methylene blue supplement suited to your needs.
In conclusion, 2025’s selection of methylene blue supplements on Amazon offers a range of options that cater to various preferences and health goals. Whether you choose a powder or capsule form, the key is to ensure that you’re making a well-informed decision based on your health needs and the essential factors addressed in this guide.
Last update on 2026-02-13 / Affiliate links / Images from Amazon Product Advertising API | hishecozy.com is a participant in the Amazon Associate program and will earn from qualifying purchases.
