In 2025, the market for cognitive enhancement continues to flourish, making nootropic supplements increasingly popular among students, professionals, and anyone seeking to enhance their mental acuity. If you’re on the lookout for the best nootropic supplement, you’re in the right place. This article will cover the top 10 products available on Amazon, ensuring you can make an informed decision based on performance, ingredients, and customer reviews.
Bestseller No. 1
ONNIT Alpha Brain Nootropic Brain Supplement for Men and Women, IGEN Non-GMO Tested, Memory, Mental Clarity, Cognitive Support and Focus Capsules with L-Theanine and Vitamin B6, 30 Count
- Focus Where it Counts: Includes one 30-count bottle of ONNIT Alpha BRAIN Nootropic Brain Supplement, IGEN certified to verify label claims about the presence of GMOs for trusted, high-quality cognitive support*
- Brain Health Supplements: ONNIT Alpha BRAIN is a dietary supplement and nootropic that helps support cognitive function, including memory, mental speed, and focus; ideal for use before exams, important meetings, or competitive gaming sessions*
- Brain Support Ingredients: Contains a distinct blend with L-Theanine, Vitamin B6, Huperzine A, Alpha GPC, and Phosphatidylserine to help your brain operate on all cylinders and support mental clarity; take daily in the morning or before mentally demanding activities*
- Caffeine-Free Nootropics: Alpha BRAIN’s effective, caffeine-free formula supports memory and focus, promotes mental processing, aids in achieving flow state, and assists mental clarity and reaction time; use at the office, at home, in the classroom, or during gaming*
- Supports High Demand Brain Function: Try Alpha BRAIN with a light meal, smoothie, or as part of your daily wellness routine to help tune out distractions, enhance clear thinking, and support deeper concentration for students, professionals, gamers, artists, and entrepreneurs*
OFF -$10.01Bestseller No. 2
FreshCap Mushrooms Ultimate Mushroom Supplement 12,000mg - Mushroom Complex Capsules, Organic Supplement Ayurveda (120 Capsules)
- NATURAL SIX MUSHROOM COMPLEX - A powerful mushroom supplement featuring Lion's Mane, Reishi, Cordyceps, Chaga, Turkey Tail, and Maitake works in synergy. Our mushroom complex capsules deliver 12,000mg raw mushroom equivalent per serving for maximum potency.
- COMPLETE WELLNESS SUPPORT - Looking for comprehensive benefits? This mushroom immune support blend maintains daily vitality while strengthening natural defenses.
- NO FILLERS, PURE INGREDIENTS - Our mushroom supplement capsules use only 100% whole fruiting body mushrooms, free from added grain or fillers. Each mushroom is triple-extracted, delivering pure and potent wellness support.
- ORGANIC, POWERFUL ACTIVE INGREDIENTS BACKED BY SCIENCE - These mushrooms herbal supplements are CCOF Certified Organic, Non-GMO, Gluten-Free, Vegan, and Paleo-friendly.
- EASY TO USE Daily Immune Support Supplement - Each bottle contains 120 capsules, providing a 2-month supply when taken at the recommended serving size of 2 capsules per day. Our easy-to-swallow capsules integrate seamlessly into your daily routine for consistent whole-body support.
OFF -$2.04Bestseller No. 3
The Genius Brand Genius Mushrooms - Plant-Based Supplement for Immune, Focus & Energy Support - Lion's Mane, Cordyceps & Reishi - Organic & Non-GMO - 90 Veggie Capsules
- Nurture: Genius Mushrooms by The Genius Brand combines 3 of the most researched mycological species on the planet that help enhance clarity, system support function, and more. Genius Mushrooms are keto, paleo, and vegan friendly. Serving size - 3 capsules, 30 servings per container
- System Booster: Step up your support with Reishi Mushroom Extract. Used for centuries, this booster is what you need to help keep yourself in check and dodge common ailments
- Caffeine-Free Energy: Lion’s Mane provides boosting benefits to support focus, function, and mood. Cordyceps helps elevate your energy levels via ATP (natural energy) production, allowing for increased oxygen utilization and athletic endurance
- How to Use: Take 3 capsules with 8 oz of water 20 minutes before a meal once a day. You may also take 1 capsule three times daily before meals, if preferred
- Supplement Smarter: Genius Brand supplements are a rejection of backwards industry dogma that misled generations of enthusiasts. For us, innovation and science-backed ingredients come first. Whether you’re a pro athlete, stay-at-home parent, retiree, or anything in between, our products can be of benefit to you. We’re all humans, and we are in this together
OFF -$7.80Bestseller No. 4
Life Extension Quick Brain Nootropic, Fast Thinking, Learning, Concentration, Lutein, zeaxanthin, gotu kola, bacopa, Gluten Free, Non-GMO, Vegetarian, 1 Daily, 30 Capsules
- Promotes mental alertness and accuracy – When it comes to supporting your mind, you don’t just want to focus on thinking fast, you want to make sure you are thinking accurately. This nootropic formula supports both for an agile mind.
- Supports learning and retention – Learning quickly and retaining what you learn is vital for navigating everyday life. The combination of lutein, zeaxanthin, gotu kola, and bacopa helps you remain focused to learn faster and improve your performance.
- Encourages faster neural processing speeds – Enhancing your mental processing speeds is another important part of keeping your mind sharp long-term. The nootropic bacopa supports improved brain processing speed and capability, as well as memory.
- Ingredients matter – We use the finest raw ingredients with the quality and purity you deserve. The majority of our products are non-GMO, gluten-free and manufactured in the USA—and a Certificate of Analysis is available for every one.
- Live your healthiest life – We believe the answers to a healthier life are in reach, and that scientific research is the key to getting there. That’s why so many of our formulas feature specific ingredients and amounts based on scientific studies.
OFF -$5.11Bestseller No. 5
NEURIVA Plus Brain Supplement for Memory and Focus Clinically Tested Nootropics for Concentration for Mental Clarity, Cognitive Enhancement Vitamins B6, B12, Phosphatidylserine 30 Capsules
- NOOTROPICS BRAIN SUPPORT SUPPLEMENT: Experience improved brain performance and unlock your full potential. Enhance your memory and focus with our clinically tested brain supplement. Formulated with coffee cherry Neurofactor, plant-sourced phosphatidylserine, and B vitamins for optimal brain health.
- CLINICALLY TESTED NEUROFACTOR FORMULA: Increase vital neuroprotein BDNF levels with our Neurofactor from whole coffee fruit extract. BDNF plays a crucial role in facilitating connections between brain cells, promoting synaptogenesis, synaptic plasticity, and neuronal survival.
- B VITAMINS: Essential for cognitive function, vitamins B6 and B12 help enhance brain energy production, neurotransmitter synthesis, and mood support, promoting overall brain well-being.
- TRUSTWORTHY AND HIGH-QUALITY INGREDIENTS: We prioritize your well-being, which is why our brain health capsules are formulated with vegetarian, gluten-free, GMO-free, and decaffeinated ingredients. Rest assured that you're consuming a premium quality supplement.
- JUST ONE CAPSULE A DAY: Adults aged 18 years and older should take one capsule daily at bedtime. This convenient serving contains all of the brain-supporting ingredients required to fuel your brain health.
Bestseller No. 6
NEURIVA Ultra Decaffeinated Clinically Tested Nootropic Brain Supplement for Mental Alertness, Memory, Focus & Concentration, Cognivive, Neurofactor, Phosphatidylserine, Vitamins B6 B12, 60 Capsules
- MEMORY AND FOCUS SUPPLEMENTS FOR ADULTS: Investing in your brain health is essential, Neuriva offers a range of brain health* supplements specially formulated to support 7 indicators of brain health.* If you need a brain boost to help you stay sharp at work or university, Neuriva has you covered with our range of brain supplements designed to promote brain health!
- BRAIN HEALTH SUPPORT FOR ADULTS: Neuriva Ultra contains clinically tested, naturally sourced, ingredients like as CogniviveTM, NeurofactorTM plus Phosphatidylserine, and B Vitamins which work together to promote optimal cognitive function and support memory and focus.*
- MENTAL ALERTNESS* WITH COGNIVIVE: A caffeine free Alpinia galanga extract that provides noticeable effects of Mental Alertness from just one serving.*
- CLINCALLY TESTED, NATURALLY SOURCED INGREDIENTS: Neuriva Ultra contains Neurofactor an extract from the amazing superfruit, coffee cherry. This powerful ingredient has been clinically tested to increase the body's levels of vital neuroprotein (BDNF), known to support connections between brain cells and plant-sourced Phosphatidylserine, which aids in neuron health and fuels memory and learning.* Pretty impressive, huh?
- B VITAMINS: With Vitamin B6, B12, and folic acid to help support brain function.*
Bestseller No. 7
Nootropic Brain Supplement for Memory and Focus Support - Vitamins for Mental Support & Clarity with Bacopa Monnieri, VIT A, B6, Riboflavin, Niacin, Thiamin & Folate - Cognitive Complex - 60 Ct
- ADVANCED BRAIN SUPPORT FOR MEMORY & FOCUS – Formulated to support cognitive function, mental clarity, and concentration, this memory supplement for brain provides essential nutrients to support memory retention, learning ability & overall brain vitality.
- HELPS MENTAL CLARITY & EASE BRAIN FOG – Our focus supplement is designed to help focus, support neurotransmitter function, and promotes cognitive performance, this brain formula promotes processing, sharper thinking & long-term mental well-being.
- POWERFUL INGREDIENTS – Featuring Bacopa Monnieri, Phosphatidylserine, DMAE, GABA, Green Tea Extract, DHA, Huperzine A, Bilberry, and essential B vitamins, this advanced memory formula works to promote healthy circulation, support neurotransmitter activity & support brain cells from oxidative stress.
- HOW TO USE & IMPORTANT WARNINGS – Take one to two nootropics capsules with food or as directed by your healthcare provider. Consult a doctor before use if you are pregnant, nursing, have a medical condition, or are taking medications that affect brain function. Not intended for children.
- MADE IN THE USA WITH GLOBALLY SOURCED INGREDIENTS – Manufactured in a GMP-compliant, ISO 17025-certified facility, our nootropics brain supplements are non-GMO. Third-party tested formula provides purity, potency & safe support for brain health and cognitive function.
Bestseller No. 8
Sapotax 17-in-1 Brain Supplement with Herbal Extracts, Vitamins & Amino Acids (60 Tablets)
- 17-in-1 Brain Supplement: Our brain supplement offers a carefully crafted blend of 17 key nutrients, meticulously formulated in a serving. This diverse mix includes vitamins, minerals, amino acids, and thoughtfully selected herbal extracts. Each ingredient has been chosen to contribute to a varied dietary intake, suitable for incorporating into your daily routine
- Enhanced Bioavailability: Our formula includes Black Pepper Extract as part of the blend for a well-rounded formula. The tablets are crafted for quick dissolution, ensuring smooth breakdown and consistent quality in every serving
- Comprehensive Nootropic Formula: Our memory supplement features a unique array of distinctive components such as L-Tyrosine, L-Theanine, Alpha-GPC, and naturally sourced caffeine from Green Tea, among others. Herbal extracts from Bacopa Monnieri, Rhodiola Rosea, Lion's Mane Mushroom, Ginkgo Biloba Leaf, Panax Ginseng Root, and Maritime Pine Bark are also included, each chosen for their beneficial properties
- Optimized for Daily Nutrition: Our nootropic brain supplement includes vitamins like Vitamin B6 and Vitamin B12, along with minerals such as Magnesium and Zinc. These ingredients are widely included in everyday nutrition and can easily be integrated into your daily lifestyle
- Quality You Can Trust: Crafted with natural, vegan-friendly, and non-GMO ingredients, our premium nootropic supplement is free from gluten, dairy, and soy. Developed with quality in mind, it meets high standards of potency and purity for reliable use
Bestseller No. 9
12-in-1 Nootropic Brain Supplement with Caffeine Anhydrous: Ginkgo Biloba for Brain Support, Memory and Focus - B12, Alpha GPC, L Theanine and Choline Supplements with Bioperine with 1321mg (60ct)
- Caffeine-Infused Memory & Focus Supplement - Keep your brain functioning at its best with our Nootropic Supplement with Caffeine, formulated to help you stay focused amidst life’s daily challenges.
- Nootropic for Your Well Being - Ideal for busy professionals and students, our memory supplement for the brain so you can easily power through the day.
- Powerful Vegan Blend - Enriched with Caffeine Anhydrous, Phosphatidylserine, Rhodiola Rosea, Bacopa Monnieri, & Bioperine for increased absorption, our nootropic brain supplement acts as a memory & focus aid to help you beat brain fog.
- Quality Brain Vitamins for Adults - Our brain supplements for memory and focus boasts a potent 1321mg blend and are formulated vegan, gluten-free. Enjoy the benefits of our memory vitamins with just 2 caps a day.
- A Nootropic Supplement You Can Trust - MedChoice supplements for brain function are 3rd party lab-tested in a GMP-certified facility. Reach out to us if you’re unhappy with your purchase.
Bestseller No. 10
17-in-1 Brain Supplement for Memory and Focus | Natural Nootropics Brain Supplement for Brain Cognition, Energy | High Absorption | L-Theanine, Phytonutrient Blend and Vitamins B6, B12 | 60 Tablets
- ADVANCED COGNITIVE FORMULA: Our brain supplement contains premium ingredients, including L-Tyrosine, L-Theanine, Alpha-GPC and Theacrine, carefully combined to provide a well-rounded blend of nutrients in a brain-focused supplement
- ENERGIZE & FOCUS WITHOUT JITTERS: Our nootropics brain supplement features a carefully crafted blend of natural nootropics like Green Tea Caffeine, Lion's Mane Mushroom, Ginkgo Biloba Leaf, Bacopa Monnieri, Rhodiola Rosea, Panax Ginseng Root, Maritime Pine Bark, 5-HTP. This phytonutrient blend is beneficial to a calm and steady state of alertness throughout the day
- HIGH BIOAVAILABILITY: Each serving is fortified with Black Pepper Extract for better absorption and effectiveness of every ingredient, allowing you to get the most out of each tablet
- HOLISTIC WELL-BEING: Our unique formula provides several vitamins and minerals like Vitamins B6, B12, Magnesium and Zinc. With a focus on a lifestyle of wellness, this holistic approach is designed to provide comprehensive benefits for overall vigor
- SAFE, NATURAL, AND NON-HABIT FORMING: Crafted from natural sources and non-habit-forming ingredients, AddiZen is a safe and reliable brain supplement for memory and focus, designed for consistent, daily use and free from concerns of dependency
Top 10 Nootropic Supplements on Amazon
1. Alpha Brain by Onnit
Overview
Alpha Brain is one of the most renowned nootropic supplements on the market. It boosts memory, focus, and cognitive processing speed.
Key Ingredients
Alpha Brain contains L-theanine, L-tyrosine, and Bacopa Monnieri, all known for their cognitive-enhancing properties.
Benefits
- Improves memory recall
- Enhances focus
- Promotes mental clarity
Customer Reviews
Users rave about its ability to boost productivity without the jitters often associated with caffeine-laden supplements.
Bestseller No. 1
ONNIT Alpha Brain Nootropic Brain Supplement for Men and Women, IGEN Non-GMO Tested, Memory, Mental Clarity, Cognitive Support and Focus Capsules with L-Theanine and Vitamin B6, 30 Count
- Focus Where it Counts: Includes one 30-count bottle of ONNIT Alpha BRAIN Nootropic Brain Supplement, IGEN certified to verify label claims about the presence of GMOs for trusted, high-quality cognitive support*
- Brain Health Supplements: ONNIT Alpha BRAIN is a dietary supplement and nootropic that helps support cognitive function, including memory, mental speed, and focus; ideal for use before exams, important meetings, or competitive gaming sessions*
- Brain Support Ingredients: Contains a distinct blend with L-Theanine, Vitamin B6, Huperzine A, Alpha GPC, and Phosphatidylserine to help your brain operate on all cylinders and support mental clarity; take daily in the morning or before mentally demanding activities*
- Caffeine-Free Nootropics: Alpha BRAIN’s effective, caffeine-free formula supports memory and focus, promotes mental processing, aids in achieving flow state, and assists mental clarity and reaction time; use at the office, at home, in the classroom, or during gaming*
- Supports High Demand Brain Function: Try Alpha BRAIN with a light meal, smoothie, or as part of your daily wellness routine to help tune out distractions, enhance clear thinking, and support deeper concentration for students, professionals, gamers, artists, and entrepreneurs*
2. Mind Lab Pro
Overview
Mind Lab Pro is marketed as a universal nootropic, suitable for anyone from students to seniors.
Key Ingredients
It includes L-theanine, Rhodiola Rosea, and Lion’s Mane Mushroom.
Benefits
- Enhances executive functions
- Increases mental energy
- Reduces stress and anxiety
Customer Reviews
Many users highlight the mental clarity and energy boost without crashes.
Bestseller No. 1
Mind Lab Pro® MLP® v4 Universal Nootropic™ Brain Booster Supplement for Focus, Memory, Clarity, Energy - 60-Count - Plant-Based, Naturally Sourced Memory Vitamins for Better Brain Health, Made in USA
- Unlock 100% of Your Brainpower - Our nootropic supplement aims to deliver a mental performance state that “fires on all cylinders” - this brain supplement acts as a memory and mood booster that can help enhance focus, motivation, and drive.
- Eliminate Mental Fatigue and Cognitive Exhaustion - Formulated to boost brain circulation, brain plasticity, and production of Alpha-frequency waves for calm alertness and clarity. Our health supplements assist in countering the effects of toxins and alleviating fatigue.
- Enjoy Enhanced Productivity With An Easy Brain Boost - Mind Lab memory supplements are for anyone seeking to improve test-taking performance, focus at work, concentration, or mental processing speed.
- 11 Evidence-Based Nootropics In Every Focus Supplement - With brain boosting ingredients like Lion's Mane mushroom, L-Theanine, Vitamins B6, B9, and B12, and a patented form of Citicoline, these brain pills are powerful, potent, and pure.
- Naturally Sourced, Plant-Based, and Easily Absorbed - Each nootropics brain supplement is made from 100% natural vegan tapioca and is bio-available. Gluten and lactose-free; no GMO, caffeine, or pointless synthetic additives.
3. Qualia Mind
Overview
Qualia Mind focuses not only on cognitive enhancement but also on overall brain health.
Key Ingredients
This supplement features a cocktail of over 28 ingredients including vitamins, amino acids, and herbal extracts.
Benefits
- Supports long-term brain health
- Improves focus and mental clarity
- Boosts mood and productivity
Customer Reviews
Users often note a notable increase in creativity and cognitive function.
Bestseller No. 1
QUALIA MIND | The Ultimate Blend For Brain Health* | Doctor-Formulated Nootropic To Fuel Focus & Concentration* | Supports Long Term Brain Health| Maintain Drive & Productivity | 2 Month Supply
- FUEL FOCUS, DRIVE & PRODUCTIVITY: Qualia Mind doctor-formulated blend of the world’s most premium brain nutrients delivers extraordinary and fast-acting changes to mindset and motivation, fueling focus, and offering support for stress-related mental fatigue, to empower new heights of productivity, achievement, and accomplishment.
4. Neurohacker Collective’s Eternus
Overview
Eternus employs an advanced blend for better brain performance and longevity.
Key Ingredients
Includes Pterostilbene, DHA, and other brain-supportive ingredients.
Benefits
- Enhances cognitive function
- Supports overall brain health
- Promotes longevity
Customer Reviews
Many customers appreciate the comprehensive formula aimed at nurturing brain health over the long term.
Bestseller No. 1
Qualia Mind — Beat Brain Fog | Doctor-Formulated Premium Brain Nourishment | Fuel Focus, Drive & Energy | 32 Ingredients Including Lion’s Mane, Cognizin™️, Ginkgo & More| 3 Week Supply*
- FUEL FOCUS, DRIVE & PRODUCTIVITY: Qualia Mind doctor-formulated blend of the world’s most premium brain nutrients delivers extraordinary and fast-acting changes to mindset and motivation, fueling focus, and offering support for stress-related mental fatigue, to empower new heights of productivity, achievement, and accomplishment.
5. SuperBrain by 1st Phorm
Overview
SuperBrain provides a well-rounded approach to cognitive enhancement, appealing to fitness enthusiasts and professionals alike.
Key Ingredients
Contains caffeine, L-theanine, and Huperzine A.
Benefits
- Delivers sharp focus and energy
- Reduces cognitive fog
- Enhances memory retention
Customer Reviews
Users appreciate its fast-acting formula that powers through tasks without overwhelming energy spikes.
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6. NooCube
Overview
NooCube is designed to not only stimulate cognitive function but also improve overall brain health.
Key Ingredients
Features a mix of L-theanine, Bacopa Monnieri, and Cat’s Claw.
Benefits
- Boosts overall cognitive performance
- Improves mood
- Supports long-term memory
Customer Reviews
Consumers appreciate its non-stimulating formula that helps with focus without jitters.
Bestseller No. 1
Brain Productivity Pills, Cognitive Enhancer Supplement, 300 caps
- Cognitive Enhancement: Noo-cube brain productivity pills are designed to boost mental focus, clarity, and concentration for improved cognitive function.
- Nootropic Formula: This brain supplement contains a blend of natural ingredients like Bacopa Monnieri, L-Theanine, and Rhodiola Rosea to support brain health.
- Increased Productivity: By enhancing mental alertness and reducing brain fog, these pills aim to maximize your productivity and work efficiency.
- Convenient Dosage: Each bottle contains 120 capsules, providing a one-month supply when taken as directed.
- Quality Assurance: Noo-cube brain productivity pills are manufactured in an FDA-registered facility adhering to strict quality control standards.
7. Nootrogen
Overview
Nootrogen is designed for optimum brain function, perfect for gamers and students.
Key Ingredients
Featuring Alpha GPC, Vinca Minor, and Ginkgo Biloba.
Benefits
- Enhances multi-tasking abilities
- Improves short-term memory
- Reduces mental fatigue
Customer Reviews
Gamers particularly love the boost in focus and reaction time during long gaming sessions.
Bestseller No. 1
ONNIT Alpha Brain Nootropic Brain Supplement for Men and Women, IGEN Non-GMO Tested, Memory, Mental Clarity, Cognitive Support and Focus Capsules with L-Theanine and Vitamin B6, 90 Count
- Focus Where it Counts: Includes one 90-count bottle of ONNIT Alpha BRAIN Nootropic Brain Supplement, IGEN certified to verify label claims about the presence of GMOs for trusted, high-quality cognitive support*
- Brain Health Supplements: ONNIT Alpha BRAIN is a dietary supplement and nootropic that helps support cognitive function, including memory, mental speed, and focus; ideal for use before exams, important meetings, or competitive gaming sessions*
- Brain Support Ingredients: Contains a distinct blend with L-Theanine, Vitamin B6, Huperzine A, Alpha GPC, and Phosphatidylserine to help your brain operate on all cylinders and support mental clarity; take daily in the morning or before mentally demanding activities*
- Caffeine-Free Nootropics: Alpha BRAIN's effective, caffeine-free formula supports memory and focus, promotes mental processing, aids in achieving flow state, and assists mental clarity and reaction time; use at the office, at home, in the classroom, or during gaming*
- Supports High Demand Brain Function: Try Alpha BRAIN with a light meal, smoothie, or as part of your daily wellness routine to help tune out distractions, enhance clear thinking, and support deeper concentration for students, professionals, gamers, artists, and entrepreneurs
8. Genius Consciousness by The Genius Brand
Overview
This product combines effective ingredients to foster cognitive function and brain health.
Key Ingredients
Includes Lion’s Mane, L-Tyrosine, and Rhodiola Rosea.
Benefits
- Regulates mood
- Promotes mental clarity
- Fuels cognitive performance
Customer Reviews
Users frequently note improvements in mood and focus, making this a favorite among professionals.
Bestseller No. 1
Genius Consciousness - Premium Nootropic Powder for Focus, Memory & Mental Clarity - AlphaSize, NeuroFactor, Lion’s Mane & Dynamine - Natural Brain Booster for Studying, Work & Creativity – Watermelon
- Brain Productivity Supplement: The Genius Brand's Genius Consciousness is a daily brain supplement crafted with premium ingredients for high-performance thinking*
- Clarity-Support Supplement: Powered by nootropics, this focus supplement is designed to support sustained concentration and clear thinking throughout your day*
- Long-Lasting Energy Supplement: Crafted with lion's mane and other natural ingredients, this no-crash energy supplement offers anti-fatigue and memory support*
- Creative Thinking Supplement : This all-in-one brain health supplement supports creativity and is manufactured in an NSF-certified facility in the USA with no proprietary blends, so you know exactly what you're getting*
- Power in Nature: The Genius Brand is dedicated to pursuing the best ingredients we can source from nature, following modern science all the while
9. Focus Factor
Overview
Focus Factor has been in the market for years, garnering a loyal customer base.
Key Ingredients
Combines vitamins, minerals, and a proprietary blend of ingredients for cognitive health.
Benefits
- Boosts focus and memory
- Provides essential nutrients
- Promotes brain function
Customer Reviews
Many longtime users cite improvements in productivity and mental clarity over extended use.
Bestseller No. 1
Focus Factor Adults Extra Strength, 120 Count - Brain Supplement for Memory, Concentration and Focus - Complete Multivitamin with DMAE, Vitamin D, DHA - Trusted Health Vitamins
- COMPLETE MULTIVITAMIN IMPROVES FOCUS: Focus Factor Extra Strength brain supplements contain a powerful combination of vitamins, minerals, and neuro-nutrients, that not only power your brain but can also replace your daily multivitamin
- PROMOTES CONCENTRATION and MEMORY: Like other parts of your body, your brain needs proper nutrition to perform its best. This advanced formula improves and enhances memory, concentration, and your ability to focus
- PREMIUM INGREDIENTS: Focus Factor brain support supplements are enriched with a powerful combination of premium ingredients like bacopa, ginkgo biloba, phosphatidylserine, DMAE, and a comprehensive blend of vitamins and minerals
- QUALITY FORMULA: Focus Factor Extra Strength takes the original Focus Factor formula and increases the levels of key selected neuro-nutrients. Our brain focus formula contains no artificial colorings or sweeteners
- FOCUS FACTOR: We offer a range of products designed to help you find your focus. Focus Factor has been America’s brain health supplement brand for nearly 20 years, with formulas for the whole family
10. Prevagen
Overview
Prevagen is especially known for its claims to support memory and cognitive function, particularly in older adults.
Key Ingredients
It contains Apoaequorin, a protein derived from jellyfish.
Benefits
- Supports memory
- Enhances cognitive function
- May help with age-related memory decline
Customer Reviews
While results can vary, many users appreciate its gentle yet effective approach to brain health.
OFF -$9.95Bestseller No. 1
Prevagen Extra Strength - 60 Capsules (2 Month Supply) | Formulated for Your Brain | 20mg of Apoaequorin Plus Vitamin D3
- For Your Brain: Prevagen Extra Strength is for your brain and comes in an easy to swallow capsule. For best results, just take ONE A DAY, in the morning, with or without food.
- Unique & Safe Ingredient: Apoaequorin, the unique ingredient in Prevagen, is a supplement formulated for your brain and has undergone extensive Safety Testing. Tests for allergenicity and toxicity have been conducted. Third party experts agree that PREVAGEN IS SAFE.
- Once Daily: A once daily and easy to swallow capsule formulated for your brain.
- #1 Selling Brain* Supplement NATIONWIDE For Over 10 Years. Prevagen, Inc. calculation based on Syndicated US NIQ Total Store including Fresh – 10 years database for the Mental Performance (Brain) Supplement category/segment last 10 years, week ending March 22, 2025 time period. Copyright (c) 2025, Nielsen Consumer LLC.
- Attractive Prevagen Box: Prevagen bottles come in an attractive, easily stackable, lightweight, and sturdy Prevagen branded box. Great for storing unused Prevagen! This unique box makes gifting Prevagen to friends and family easy.
Buying Guide: How to Choose the Best Nootropic Supplement
Choosing the right nootropic supplement can be daunting with so many options available today. Here are a few important factors to consider:
Ingredients
Look for well-studied ingredients known to boost cognitive function, such as L-theanine, Bacopa Monnieri, and Rhodiola Rosea. Always check for a comprehensive ingredient list to ensure there are no hidden additives.
Dosage
Ensure the dosages of the key ingredients are backed by scientific studies. High-quality products will include effective dosages for their active ingredients.
Customer Reviews and Reputation
Check customer reviews on Amazon and other platforms. A supplement with a high number of positive reviews is often an indicator of its effectiveness.
Third-Party Testing
Opt for brands that provide third-party testing. This ensures the product’s quality, potency, and purity, which is essential in any supplement.
Price
While a higher price does not always equate to better quality, be wary of extremely low-cost products; they might skimp on quality ingredients.
Personal Needs
Lastly, consider what you specifically need from a nootropic supplement. Whether you aim to improve focus, memory, or mood, select a product that aligns with your goals.
Conclusion
In 2025, the best nootropic supplement can significantly impact your cognitive function, empower you to perform better at school or work, and improve your overall mental well-being. The products mentioned above are among the top-rated on Amazon, ensuring quality, effectiveness, and customer satisfaction. Remember to review your unique needs and do adequate research before making a purchase.
Bestseller No. 1
ONNIT Alpha Brain Nootropic Brain Supplement for Men and Women, IGEN Non-GMO Tested, Memory, Mental Clarity, Cognitive Support and Focus Capsules with L-Theanine and Vitamin B6, 30 Count
- Focus Where it Counts: Includes one 30-count bottle of ONNIT Alpha BRAIN Nootropic Brain Supplement, IGEN certified to verify label claims about the presence of GMOs for trusted, high-quality cognitive support*
- Brain Health Supplements: ONNIT Alpha BRAIN is a dietary supplement and nootropic that helps support cognitive function, including memory, mental speed, and focus; ideal for use before exams, important meetings, or competitive gaming sessions*
- Brain Support Ingredients: Contains a distinct blend with L-Theanine, Vitamin B6, Huperzine A, Alpha GPC, and Phosphatidylserine to help your brain operate on all cylinders and support mental clarity; take daily in the morning or before mentally demanding activities*
- Caffeine-Free Nootropics: Alpha BRAIN’s effective, caffeine-free formula supports memory and focus, promotes mental processing, aids in achieving flow state, and assists mental clarity and reaction time; use at the office, at home, in the classroom, or during gaming*
- Supports High Demand Brain Function: Try Alpha BRAIN with a light meal, smoothie, or as part of your daily wellness routine to help tune out distractions, enhance clear thinking, and support deeper concentration for students, professionals, gamers, artists, and entrepreneurs*
OFF -$10.01Bestseller No. 2
FreshCap Mushrooms Ultimate Mushroom Supplement 12,000mg - Mushroom Complex Capsules, Organic Supplement Ayurveda (120 Capsules)
- NATURAL SIX MUSHROOM COMPLEX - A powerful mushroom supplement featuring Lion's Mane, Reishi, Cordyceps, Chaga, Turkey Tail, and Maitake works in synergy. Our mushroom complex capsules deliver 12,000mg raw mushroom equivalent per serving for maximum potency.
- COMPLETE WELLNESS SUPPORT - Looking for comprehensive benefits? This mushroom immune support blend maintains daily vitality while strengthening natural defenses.
- NO FILLERS, PURE INGREDIENTS - Our mushroom supplement capsules use only 100% whole fruiting body mushrooms, free from added grain or fillers. Each mushroom is triple-extracted, delivering pure and potent wellness support.
- ORGANIC, POWERFUL ACTIVE INGREDIENTS BACKED BY SCIENCE - These mushrooms herbal supplements are CCOF Certified Organic, Non-GMO, Gluten-Free, Vegan, and Paleo-friendly.
- EASY TO USE Daily Immune Support Supplement - Each bottle contains 120 capsules, providing a 2-month supply when taken at the recommended serving size of 2 capsules per day. Our easy-to-swallow capsules integrate seamlessly into your daily routine for consistent whole-body support.
OFF -$2.04Bestseller No. 3
The Genius Brand Genius Mushrooms - Plant-Based Supplement for Immune, Focus & Energy Support - Lion's Mane, Cordyceps & Reishi - Organic & Non-GMO - 90 Veggie Capsules
- Nurture: Genius Mushrooms by The Genius Brand combines 3 of the most researched mycological species on the planet that help enhance clarity, system support function, and more. Genius Mushrooms are keto, paleo, and vegan friendly. Serving size - 3 capsules, 30 servings per container
- System Booster: Step up your support with Reishi Mushroom Extract. Used for centuries, this booster is what you need to help keep yourself in check and dodge common ailments
- Caffeine-Free Energy: Lion’s Mane provides boosting benefits to support focus, function, and mood. Cordyceps helps elevate your energy levels via ATP (natural energy) production, allowing for increased oxygen utilization and athletic endurance
- How to Use: Take 3 capsules with 8 oz of water 20 minutes before a meal once a day. You may also take 1 capsule three times daily before meals, if preferred
- Supplement Smarter: Genius Brand supplements are a rejection of backwards industry dogma that misled generations of enthusiasts. For us, innovation and science-backed ingredients come first. Whether you’re a pro athlete, stay-at-home parent, retiree, or anything in between, our products can be of benefit to you. We’re all humans, and we are in this together
OFF -$7.80Bestseller No. 4
Life Extension Quick Brain Nootropic, Fast Thinking, Learning, Concentration, Lutein, zeaxanthin, gotu kola, bacopa, Gluten Free, Non-GMO, Vegetarian, 1 Daily, 30 Capsules
- Promotes mental alertness and accuracy – When it comes to supporting your mind, you don’t just want to focus on thinking fast, you want to make sure you are thinking accurately. This nootropic formula supports both for an agile mind.
- Supports learning and retention – Learning quickly and retaining what you learn is vital for navigating everyday life. The combination of lutein, zeaxanthin, gotu kola, and bacopa helps you remain focused to learn faster and improve your performance.
- Encourages faster neural processing speeds – Enhancing your mental processing speeds is another important part of keeping your mind sharp long-term. The nootropic bacopa supports improved brain processing speed and capability, as well as memory.
- Ingredients matter – We use the finest raw ingredients with the quality and purity you deserve. The majority of our products are non-GMO, gluten-free and manufactured in the USA—and a Certificate of Analysis is available for every one.
- Live your healthiest life – We believe the answers to a healthier life are in reach, and that scientific research is the key to getting there. That’s why so many of our formulas feature specific ingredients and amounts based on scientific studies.
OFF -$5.11Bestseller No. 5
NEURIVA Plus Brain Supplement for Memory and Focus Clinically Tested Nootropics for Concentration for Mental Clarity, Cognitive Enhancement Vitamins B6, B12, Phosphatidylserine 30 Capsules
- NOOTROPICS BRAIN SUPPORT SUPPLEMENT: Experience improved brain performance and unlock your full potential. Enhance your memory and focus with our clinically tested brain supplement. Formulated with coffee cherry Neurofactor, plant-sourced phosphatidylserine, and B vitamins for optimal brain health.
- CLINICALLY TESTED NEUROFACTOR FORMULA: Increase vital neuroprotein BDNF levels with our Neurofactor from whole coffee fruit extract. BDNF plays a crucial role in facilitating connections between brain cells, promoting synaptogenesis, synaptic plasticity, and neuronal survival.
- B VITAMINS: Essential for cognitive function, vitamins B6 and B12 help enhance brain energy production, neurotransmitter synthesis, and mood support, promoting overall brain well-being.
- TRUSTWORTHY AND HIGH-QUALITY INGREDIENTS: We prioritize your well-being, which is why our brain health capsules are formulated with vegetarian, gluten-free, GMO-free, and decaffeinated ingredients. Rest assured that you're consuming a premium quality supplement.
- JUST ONE CAPSULE A DAY: Adults aged 18 years and older should take one capsule daily at bedtime. This convenient serving contains all of the brain-supporting ingredients required to fuel your brain health.
Bestseller No. 6
NEURIVA Ultra Decaffeinated Clinically Tested Nootropic Brain Supplement for Mental Alertness, Memory, Focus & Concentration, Cognivive, Neurofactor, Phosphatidylserine, Vitamins B6 B12, 60 Capsules
- MEMORY AND FOCUS SUPPLEMENTS FOR ADULTS: Investing in your brain health is essential, Neuriva offers a range of brain health* supplements specially formulated to support 7 indicators of brain health.* If you need a brain boost to help you stay sharp at work or university, Neuriva has you covered with our range of brain supplements designed to promote brain health!
- BRAIN HEALTH SUPPORT FOR ADULTS: Neuriva Ultra contains clinically tested, naturally sourced, ingredients like as CogniviveTM, NeurofactorTM plus Phosphatidylserine, and B Vitamins which work together to promote optimal cognitive function and support memory and focus.*
- MENTAL ALERTNESS* WITH COGNIVIVE: A caffeine free Alpinia galanga extract that provides noticeable effects of Mental Alertness from just one serving.*
- CLINCALLY TESTED, NATURALLY SOURCED INGREDIENTS: Neuriva Ultra contains Neurofactor an extract from the amazing superfruit, coffee cherry. This powerful ingredient has been clinically tested to increase the body's levels of vital neuroprotein (BDNF), known to support connections between brain cells and plant-sourced Phosphatidylserine, which aids in neuron health and fuels memory and learning.* Pretty impressive, huh?
- B VITAMINS: With Vitamin B6, B12, and folic acid to help support brain function.*
Bestseller No. 7
Nootropic Brain Supplement for Memory and Focus Support - Vitamins for Mental Support & Clarity with Bacopa Monnieri, VIT A, B6, Riboflavin, Niacin, Thiamin & Folate - Cognitive Complex - 60 Ct
- ADVANCED BRAIN SUPPORT FOR MEMORY & FOCUS – Formulated to support cognitive function, mental clarity, and concentration, this memory supplement for brain provides essential nutrients to support memory retention, learning ability & overall brain vitality.
- HELPS MENTAL CLARITY & EASE BRAIN FOG – Our focus supplement is designed to help focus, support neurotransmitter function, and promotes cognitive performance, this brain formula promotes processing, sharper thinking & long-term mental well-being.
- POWERFUL INGREDIENTS – Featuring Bacopa Monnieri, Phosphatidylserine, DMAE, GABA, Green Tea Extract, DHA, Huperzine A, Bilberry, and essential B vitamins, this advanced memory formula works to promote healthy circulation, support neurotransmitter activity & support brain cells from oxidative stress.
- HOW TO USE & IMPORTANT WARNINGS – Take one to two nootropics capsules with food or as directed by your healthcare provider. Consult a doctor before use if you are pregnant, nursing, have a medical condition, or are taking medications that affect brain function. Not intended for children.
- MADE IN THE USA WITH GLOBALLY SOURCED INGREDIENTS – Manufactured in a GMP-compliant, ISO 17025-certified facility, our nootropics brain supplements are non-GMO. Third-party tested formula provides purity, potency & safe support for brain health and cognitive function.
Bestseller No. 8
Sapotax 17-in-1 Brain Supplement with Herbal Extracts, Vitamins & Amino Acids (60 Tablets)
- 17-in-1 Brain Supplement: Our brain supplement offers a carefully crafted blend of 17 key nutrients, meticulously formulated in a serving. This diverse mix includes vitamins, minerals, amino acids, and thoughtfully selected herbal extracts. Each ingredient has been chosen to contribute to a varied dietary intake, suitable for incorporating into your daily routine
- Enhanced Bioavailability: Our formula includes Black Pepper Extract as part of the blend for a well-rounded formula. The tablets are crafted for quick dissolution, ensuring smooth breakdown and consistent quality in every serving
- Comprehensive Nootropic Formula: Our memory supplement features a unique array of distinctive components such as L-Tyrosine, L-Theanine, Alpha-GPC, and naturally sourced caffeine from Green Tea, among others. Herbal extracts from Bacopa Monnieri, Rhodiola Rosea, Lion's Mane Mushroom, Ginkgo Biloba Leaf, Panax Ginseng Root, and Maritime Pine Bark are also included, each chosen for their beneficial properties
- Optimized for Daily Nutrition: Our nootropic brain supplement includes vitamins like Vitamin B6 and Vitamin B12, along with minerals such as Magnesium and Zinc. These ingredients are widely included in everyday nutrition and can easily be integrated into your daily lifestyle
- Quality You Can Trust: Crafted with natural, vegan-friendly, and non-GMO ingredients, our premium nootropic supplement is free from gluten, dairy, and soy. Developed with quality in mind, it meets high standards of potency and purity for reliable use
Bestseller No. 9
12-in-1 Nootropic Brain Supplement with Caffeine Anhydrous: Ginkgo Biloba for Brain Support, Memory and Focus - B12, Alpha GPC, L Theanine and Choline Supplements with Bioperine with 1321mg (60ct)
- Caffeine-Infused Memory & Focus Supplement - Keep your brain functioning at its best with our Nootropic Supplement with Caffeine, formulated to help you stay focused amidst life’s daily challenges.
- Nootropic for Your Well Being - Ideal for busy professionals and students, our memory supplement for the brain so you can easily power through the day.
- Powerful Vegan Blend - Enriched with Caffeine Anhydrous, Phosphatidylserine, Rhodiola Rosea, Bacopa Monnieri, & Bioperine for increased absorption, our nootropic brain supplement acts as a memory & focus aid to help you beat brain fog.
- Quality Brain Vitamins for Adults - Our brain supplements for memory and focus boasts a potent 1321mg blend and are formulated vegan, gluten-free. Enjoy the benefits of our memory vitamins with just 2 caps a day.
- A Nootropic Supplement You Can Trust - MedChoice supplements for brain function are 3rd party lab-tested in a GMP-certified facility. Reach out to us if you’re unhappy with your purchase.
Bestseller No. 10
17-in-1 Brain Supplement for Memory and Focus | Natural Nootropics Brain Supplement for Brain Cognition, Energy | High Absorption | L-Theanine, Phytonutrient Blend and Vitamins B6, B12 | 60 Tablets
- ADVANCED COGNITIVE FORMULA: Our brain supplement contains premium ingredients, including L-Tyrosine, L-Theanine, Alpha-GPC and Theacrine, carefully combined to provide a well-rounded blend of nutrients in a brain-focused supplement
- ENERGIZE & FOCUS WITHOUT JITTERS: Our nootropics brain supplement features a carefully crafted blend of natural nootropics like Green Tea Caffeine, Lion's Mane Mushroom, Ginkgo Biloba Leaf, Bacopa Monnieri, Rhodiola Rosea, Panax Ginseng Root, Maritime Pine Bark, 5-HTP. This phytonutrient blend is beneficial to a calm and steady state of alertness throughout the day
- HIGH BIOAVAILABILITY: Each serving is fortified with Black Pepper Extract for better absorption and effectiveness of every ingredient, allowing you to get the most out of each tablet
- HOLISTIC WELL-BEING: Our unique formula provides several vitamins and minerals like Vitamins B6, B12, Magnesium and Zinc. With a focus on a lifestyle of wellness, this holistic approach is designed to provide comprehensive benefits for overall vigor
- SAFE, NATURAL, AND NON-HABIT FORMING: Crafted from natural sources and non-habit-forming ingredients, AddiZen is a safe and reliable brain supplement for memory and focus, designed for consistent, daily use and free from concerns of dependency
As the demand for cognitive enhancement continues to rise, investing in the best nootropic supplement can offer both immediate and long-term cognitive benefits.
Last update on 2025-12-26 / Affiliate links / Images from Amazon Product Advertising API | hishecozy.com is a participant in the Amazon Associate program and will earn from qualifying purchases.
